Results 141 to 150 of about 10,923,960 (347)
Decoupling chromatin hubs from gene control
Nature Structural & Molecular BiologyD.G.L. is supported by the European Research Council (grant no. 101045439, 3D-REVOLUTION) and the Spanish “Agencia Estatal de Investigación” (grant no. PID2022-143253NB-I00/ AEI/10.13039/501100011033/ FEDER, UE). Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of ...
openaire +3 more sources
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Identification of hub genes and pathways in glioblastoma by bioinformatics analysis
Oncology Letters, 2018 Glioblastoma (GBM) is the most common type of malignant brain tumor, and is associated with poor patient prognosis. A comprehensive understanding of the molecular mechanism underlying GBM may help to guide the identification of novel diagnoses and treatment targets.
Yang, Shoubo, Gao, Kaidi, Li, Wenbin
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
bianlab-hub/Wang_Cell_Reports_2023: Wang_Cell_Reports_2023_v1.1.0
, 2023 No description ...
bianlab-hub
core +1 more source
Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma
EBioMedicine, 2018 Recent technological advancements have permitted high-throughput measurement of the human genome, epigenome, metabolome, transcriptome, and proteome at the population level.
Zhaoxi Wang +26 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Student Opinion Survey (ECOA) Collection
This collection contains curated research educational data generated by the Living Lab & Data Hub from the Institute for the Future of Education. This data is available, on-demand, for researchers from Tecnologico de Monterrey and for researchers from ...
IFE Data Hub
core +1 more source