Results 131 to 140 of about 10,923,960 (347)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Co-Expression Network Analysis and Hub Gene Selection for High-Quality Fiber in Upland Cotton (Gossypium hirsutum) Using RNA Sequencing Analysis

Genes, 2019
Upland cotton (Gossypium hirsutum) is grown for its elite fiber. Understanding differential gene expression patterns during fiber development will help to identify genes associated with fiber quality.
Xian-yan Zou, Ai-Ying Liu, Zhen Zhang, Qun Ge, S. Fan, Wan-Kui Gong, Junwen Li, Juwu Gong, Yuzhen Shi, Bao-Ming Tian, Yan-Ling Wang, Rui-Xian Liu, K. Lei, Qí Zhāng, Xiao Jiang, Yu-Long Feng, Shu-Ya Zhang, Tingting Jia, Li-Peng Zhang, You-Lu Yuan, H. Shang   +20 more
semanticscholar   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Identify the hub gene.

, 2021
A. Use STRING online database to build a PPI network that interacts with DYNC1I1; B. Use Cyto-Hubba software to identify the hub gene. DYNC1I1 was the only hub gene that intersects among the top 100 genes obtained by each of the 11 algorithms.
Sihuan Xu (11597029), Xin Li (51274), Kun Liu (148201), Jian Zhou (28020), Junfang Hu (11597032), Yan Liu (25061), Songlin Ma (11597026), Yi Li (1144), Yue Zhu (306128), Li Li (14993)   +9 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Increased expression of hub gene CXCL10 in peripheral blood mononuclear cells of patients with systemic lupus erythematosus

Experimental and Therapeutic Medicine, 2019
Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease, characterized by overactive inflammation and aberrant activation of lymphocytes.
Rui-Xian Zhang, Ya Li, B. Pan, Yi Li, Aimin Liu, Xiaolan Li   +5 more
semanticscholar   +1 more source

Exploring protein profiles and hub genes in ameloblastoma

Biomedical Reports
Ameloblastoma (AM) is a prominent benign odontogenic tumor characterized by aggressiveness, likely originating from tooth-generating tissue or the dental follicle (DF). However, proteomic distinctions between AM and DF remain unclear. In the present study, the aim was to identify the distinction between AM and DF in terms of their proteome and to ...
Sanguansin, Sirima, Kengkarn, Sudaporn, Klongnoi, Boworn, Chujan, Suthipong, Roytrakul, Sittirak, Kitkumthorn, Nakarin   +5 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

bianlab-hub/Wang_Cell_Reports_2023: Wang_Cell_Reports_2023_v1.0.0

, 2023
No description ...
bianlab-hub
core   +1 more source

Assessment of Sleep Effects of Flaxseed Consumption: a System Biology Study [PDF]

Research Journal of Pharmacognosy
Background and objectives: Flaxseed (Linum usitatissimum L.) as an outstanding food with beneficial properties contains omega-3 fatty acids, lignans, α-linolenic acid, and digestible proteins.
Hajar Sadat Sadeghi, Roshanak Mokaberinejad, Mostafa Rezaei-Tavirani*   +2 more
doaj   +1 more source