Results 171 to 180 of about 8,236,393 (357)

Parkinson Disease Subtype Stability and Eventual Convergence

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok, Christina N. Lessov‐Schlaggar, Abdulmunaim M. Eid, Erin R. Foster, Baijayanta Maiti, Hailee Domash, Helen Hwang, Richard J. Perrin, Paul T. Kotzbauer, Joel S. Perlmutter, Meghan C. Campbell   +10 more
wiley   +1 more source

Summary of the candidate hub-regulation genes.

, 2018
Summary of the candidate hub-regulation genes.
Chunhua Ren (776468), Chaoqun Hu (776472), Ting Chen (15205), Hongmei Li (51944), Chuhang Cheng (6053732), Wen Huang (186929), Kaimin Cheng (6053735), Xiao Jiang (487846), Peng Luo (488595)   +8 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Identification of potential biomarkers for osteoporosis and chronic kidney disease through bioinformatics and machine learning algorithm.

PLoS ONE
ObjectiveThe purpose of this study is to identify hub genes associated with both osteoporosis (OP) and chronic kidney disease (CKD) through bioinformatics analysis, and to explore the potential pathogenetic mechanisms in OP and CKD through these hub ...
Hao Tang, Kai Hu, Yuankang He, Zihao Zhang, Bingcheng Liu, Xiao Ma, Tianwen Ye   +6 more
doaj   +1 more source

Functional enrichment of drought-responsive hub genes.

, 2012
Functional enrichment of drought-responsive hub genes.
Kaijing Zuo (161572), Lida Zhang (14681), Shunwu Yu (161566), Lijun Luo (161578), Kexuan Tang (14684)   +4 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

WGCNA modules, number of transcripts with significant correlations, hub transcription factors and hub genes.

, 2023
WGCNA modules, number of transcripts with significant correlations, hub transcription factors and hub genes.
Pengmin Wang (17008362), Claude Robert (255405), Éric R. Paquet (17008365)   +2 more
core   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

Identification of Five NK Cell-Related Hub Genes in COPD Using Single-Cell RNA Sequencing Analysis [PDF]

Xiaojie Deng,1,* Xiahui Yang,1,* Zhihua Gan,2 Huaxing Huang,1 Jun Yang1 1Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Guangzhou Medical University Guangzhou, Guangdong, People’s Republic of China ...
Yang X, Yang J, Huang H, Gan Z, Deng X
core  

Real hub gene-drug interaction network of the identified real hub genes.

, 2021
Panels A–F indicates the available chemotherapeutic drugs in CTD that decrease or increase the expression levels of the real hub genes. (A) Real hub gene-drug network of CXCL12; (B) Real hub gene-drug network of CXCL8; (C) Real hub gene-drug network of ...
Shufang Liang (781312), Muhammad Usman (1504405), Samina Ejaz (11378800), Yasir Hameed (8939681)   +3 more
core   +1 more source