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Identification of hub genes in aortic dissection based on weighted gene co-expression network analysis and Mendelian randomization study. [PDF]
Wang L +5 more
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Identifying pyroptosis-hub genes and immune infiltration in neonatal hypoxic-ischemic brain injury. [PDF]
Qin C +8 more
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Integrated bioinformatics analysis identifies RPS27A and PPP2R1A as shared hub genes in heart failure and COVID-19. [PDF]
Lang T, Liu X, Meng L.
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Association analysis of hepatocellular carcinoma‐related hub proteins and hub genes
PROTEOMICS – Clinical Applications, 2023AbstractPurposeHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The occurrence and development of HCC are closely related to epigenetic modifications. Epigenetic modifications can regulate gene expression and related functions through DNA methylation.
Xinhong Zhang +3 more
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RANKING DIFFERENTIAL HUBS IN GENE CO-EXPRESSION NETWORKS
Journal of Bioinformatics and Computational Biology, 2012Identifying the genes that change their expressions between two conditions (such as normal versus cancer) is a crucial task that can help in understanding the causes of diseases. Differential networking has emerged as a powerful approach to detect the changes in network structures and to identify the differentially connected genes among two networks ...
Omar, Odibat, Chandan K, Reddy
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Hub Genes Identification in Brain Cancer with Gene Expression Data
2020 20th International Conference on Advances in ICT for Emerging Regions (ICTer), 2020Central nervous system (CNS) cancers are one of the leading cancer types in the world. Analysing gene hubs involved in CNS cancer is important for predicting therapies. We have used gene expression data from one of the common brain cancer type (Pheochromocytoma /paraganglioma (PCPG)) for hub gene identification.
S. P. B. M Senadheera, A. R. Weerasinghe
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Weighted gene co-expression network analysis for hub genes in colorectal cancer
Pharmacological Reports, 2023This study is designed to explore hub genes participating in colorectal cancer (CRC) development through weighted gene co-expression network analysis (WGCNA).Expression profiles of CRC and normal samples were retrieved from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA), and were subjected to WGCNA to filter differentially ...
Zheng Xu, Jianing Wang, Guosheng Wang
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Spatial organization of gene expression: the active chromatin hub
Chromosome Research, 2003Developmental and tissue-specific expression of higher eukaryotic genes involves activation of transcription at the appropriate time and place and keeping it silent otherwise. Unlike housekeeping genes, tissue-specific genes generally do not cluster on the chromosomes.
de Laat, WL (Wouter), Grosveld, Frank
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