Results 61 to 70 of about 16,607 (261)

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

Stochastic Hierarchical Multimodal Hub Location Problem for Cargo Delivery Systems: Formulation and Algorithm

open access: yesIEEE Access, 2020
This study aims at developing a stochastic hierarchical multimodal hub location modeling framework for cargo delivery systems to capture uncertainty in hub construction cost and travel time at the strategic level.
Xiaoting Shang   +5 more
doaj   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

open access: yesAdvanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Designing a hub covering location problem under uncertainty conditions [PDF]

open access: yesDecision Science Letters, 2020
Mir Reza Zahedi , Javid Ghahremani Nahr
doaj   +1 more source

Hub location problems in transportation networks

open access: yesTransportation Research Part E: Logistics and Transportation Review, 2011
Abstract In this paper we propose a 4-index formulation for the uncapacitated multiple allocation hub location problem tailored for urban transport and liner shipping network design. This formulation is very tight and most of the tractable instances for MIP solvers are optimally solvable at the root node.
Gelareh, Shahin, Nickel, Stefan
openaire   +2 more sources

Tuning Li+ and Na+ Functionality in Renewable Carbon Electroactive Material Through Site‐Specific Nanostructural Disorder

open access: yesAdvanced Science, EarlyView.
This study presents a selective thermal transformation of polycarbonate into hybrid carbon materials. The structured carbon enhances electrochemical performance, particularly in lithium‐ion systems. Investigations reveal improved bimetallic ion diffusivity through the hybrid microstructure, contributing to excellent charge kinetics.
Montajar Sarkar   +7 more
wiley   +1 more source

Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro‐Vascularized Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su   +18 more
wiley   +1 more source

Dynamic + maximal hub location problem for freight transportation planning with rational markets

open access: yesAdvances in Mechanical Engineering, 2019
In this article, a dynamic maximal hub location covering problem for a freight transportation system is studied, in which the model has the possibility of having expansion scenarios for future according to the forecasts of increasing demands.
Roghayyeh Alizadeh, Tatsushi Nishi
doaj   +1 more source

Recent Advances in Sustainable Single‐Atom Catalysts from Biomass and Solid Waste: Design, Synthesis and Applications

open access: yesAdvanced Science, EarlyView.
Biomass‐ and solid waste‐derived sustainable single‐atom catalysts (Sus‐SACs) provide a cost‐effective and renewable approach to catalyst design. This review summarizes precursor selection, including AI‐assisted screening, synthesis strategies with emphasis on ultrafast methods, and advanced characterization techniques.
Hongzhe He   +8 more
wiley   +1 more source

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