Results 71 to 80 of about 263,352 (294)

A new model for the capacitated single allocation hub location-routing problem [PDF]

, 2014
International audience—We address the problem of designing a logistic system for general goods transport firms to ship goods from many origins to many destinations through routing and con-solidation via hubs.
Bostel, Nathalie, Dejax, Pierre, Zhang, Mi   +2 more
core   +1 more source

Multifunctional Bioactive Scaffold Facilitating BMSCs‐Driven Osteogenesis and Vascularization in Critical‐Sized Bone Defect Repair

Advanced Science, EarlyView.
A dual‐network bFGF@CB‐gel integrates: i) ChSMA scaffold (mechanical support/BMSCs delivery); ii) BC carrier (sustained bFGF release via EGFL/Itga2b and COMP/PI3K/AKT for adhesion/osteogenesis); iii) bFGF/PI3K/AKT/eNOS for angiogenesis. This rational, synergistic design addresses CSD bone regeneration challenges.
Yunze Feng, Bingzhi Chen, Yu Xu, Xin Xu, Bingtao Hu, Tongbo Li, Dingxin Zhang, Baoshuai Bai, Chen Liu, Wanlong Xu, Le Li, Wencan Zhang, Haipeng Si   +12 more
wiley   +1 more source

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

Advanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua, Anira Escrichs, Yonatan Sanz Perl, Morten L. Kringelbach, Adele Diamond, Solange Denervaud, Gustavo Deco   +6 more
wiley   +1 more source

Public Transit Labeling

, 2015
We study the journey planning problem in public transit networks. Developing efficient preprocessing-based speedup techniques for this problem has been challenging: current approaches either require massive preprocessing effort or provide limited ...
Delling, Daniel, Dibbelt, Julian, Pajor, Thomas, Werneck, Renato F.   +3 more
core   +1 more source

The Polymers of Life: Exploring Cellular Function Through Polymer Concepts

Advanced Science, EarlyView.
Biomolecular phase separation reveals that a hidden layer of cellular organization is governed by the principles of polymer science. This review bridges polymer physics and cell biology, offering a primer on fundamental concepts, proposing a framework for interrogating cellular function, and synthesizing biophysical methods for decoding macromolecular ...
Mark Chen, Ashutosh Chilkoti
wiley   +1 more source

Variable Neighborhood Search for Solving the Capacitated Single Allocation Hub Location Problem [PDF]

, 2013
In this paper a Variable Neighborhood Search (VNS) algorithm for solving the Capacitated Single Allocation Hub Location Problem (CSAHLP) is presented.
Maric, Miroslav
core  

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Solving the Uncapacitated Single Allocation p-Hub Median Problem on GPU

, 2017
A parallel genetic algorithm (GA) implemented on GPU clusters is proposed to solve the Uncapacitated Single Allocation p-Hub Median problem. The GA uses binary and integer encoding and genetic operators adapted to this problem.
A Ilic, AT Ernst, AT Ernst, D Bryan, EG Talbi, H Damgacioglu, H Topcuoglu, I Contreras, J Kratica, J Sohn, JF Campbell, JF Campbell, JF Campbell, JF Chen, M Labbe, M Maric, MR Silva, MW Horner, R Abyazi-Sani, RS Camargo de, S Abdinnour-Helm, T Meyer, TV Luong   +22 more
core   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Optimizing Modular Hub Location in Air and Road Transportation Systems [PDF]

Journal of Project Management
Hub networks play a crucial role in optimizing transportation costs in air and road systems. Their main objective is to strategically locate hubs and allocate non-hub nodes within the network.
Zahra Arabzadeh Nosrat Abad, Farid Momayezi   +1 more
doaj   +1 more source