Results 91 to 100 of about 505,873 (258)

ANIMAL WELFARE AND THE HUMAN-ANIMAL BOND IN STUDENT EDUCATION – HOW CAN WE UNDERSTAND ANIMAL FEELINGS? HOW DO WE ASK FOR CONSENT FROM A HORSE?

open access: yesSlovenian Veterinary Research
Students in veterinary education want positive interactions with their clients, but learn that a stressed animal can become unpredictable. If students can learn how to measure or evaluate the animal’s affective state before the physical exam, they can ...
Nichole Anderson
doaj   +1 more source

Advances in the management of obesity in dogs [PDF]

open access: yes, 2009
This article gives a short overview of the management of obesity in dogs and tells you more about the recent introduction of anti-obesity drugs. It is the authors’ opinion that no weight control programme in a veterinary practice can succeed without the ...
Holden, S.L., Ramsey, I.K.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Aspects of Sex Differences: Social Intelligence vs. Creative Intelligence [PDF]

open access: yes, 2017
In this article, we argue that there is an essential difference between social intelligence and creative intelligence, and that they have their foundation in human sexuality.
Fellmann, Ferdinand   +1 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Epidemiology of cat bites to people in Uruguay: Effects of the age and sex of the victim, season of the year and the COVID-19 pandemic

open access: yesOpen Veterinary Journal
Background: Cat bites to people are an important public health problem. However, very little information exists on the epidemiology of people bitten by cats at the level of an entire country in Latin America.
Juan Pablo Damian   +3 more
doaj   +1 more source

Aligning Pathology Assessment in a Learner-Centered Undergraduate Medical Curriculum [PDF]

open access: yes, 2017
Introduction: The Bond Medical Program delivers pathology in the preclinical years through interactive learning. Assessment for learning demands fit-for-purpose assessment that aligns with the curriculum.
Doshi, Neelam   +2 more
core   +1 more source

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