Results 101 to 110 of about 9,823,874 (240)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Assessing Cultural, Religious, and Trauma Influences in Human-Animal Interactions for Effective Animal-Assisted Counseling

open access: yesAnimals
The purpose of this manuscript is to enhance the understanding of how racial, social, and cultural factors influence animal-assisted counseling (AAC). As AAC gains popularity, there is an increasing need for clinicians to practice cultural humility and ...
Jordan Jalen Evans
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Effects of adding different levels of fructooligosaccharide to diet on productive performance, egg quality traits, immune response and blood metabolites in commercial laying hens

open access: yesVeterinary Medicine and Science
Background A prebiotic is defined as an indigestible feed substance that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the large intestine, thereby improving host health and ...
Salah Mahdi Alsherify, Ahmad Hassanabadi
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Human-Animal Bonding in Animal-Assisted Interventions in Counseling [PDF]

open access: yes, 2019
Animal-assisted interventionists incorporating an animal into clinical practice must harness the human–animal bond for therapeutic benefit. Therapists have a duty to understand the complex relational processes occurring in this modality (Stewart, Chang ...
Buechener-Maxwell, Virginia   +1 more
core  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Understanding and accessing the continuum of human/animal support services: A scoping review

open access: yesHuman-Animal Interactions
Background: Approximately 66% of US households have companion animals (CAs); the majority view them as family (American Pet Products Association, 2023–2024).
Lisa Townsend   +3 more
doaj   +1 more source

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