Results 81 to 90 of about 1,955,553 (299)

The role of the human-canine bond in recovery from substance use disorder: A scoping review and narrative synthesis

Human-Animal Interactions
Recovery from substance use disorder (SUD) is a personal journey that includes connection with self and others, including animals – known as the human-animal bond (HAB).
Colleen Dell, Brynn Kosteniuk, Carolyn Doi, Courtney Townsend, Alexis Cook, Darlene Chalmers, Peter Butt   +6 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interspecies Relational Theory: A Framework for Compassionate Interspecies Interactions

Veterinary Sciences
Most studies on relationships between humans and nonhuman animals focus on the benefits of the relationship to humans, the potential detriment or stress to animals, or how humans can better improve husbandry or handling practices in the domestic setting.
Emily Kieson
doaj   +1 more source

A focus on cross-purpose tools, automated recognition of study design in multiple disciplines, and evaluation of automation tools: a summary of significant discussions at the fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) [PDF]

, 2020
The fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) was held 5–6 November 2019 in The Hague, the Netherlands.
Glasziou, Paul, O'Connor, Annette M, Spijker, René, Taylor, Michele, Thomas, James, Wolfe, Mary S   +5 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Measurement of attachment in human-animal interaction research

Human-Animal Interactions
Researchers in the field of human-animal interaction often investigate the construct of the human-animal bond in order to measure contextual information about companion-animal relationships beyond simply living with a pet.
Eli D. Halbreich, Tristen D. Hefner, Ashly S. Healy, Jason Van Allen   +3 more
doaj   +1 more source

Evaluation of owners’ attitudes towards veterinarian attire in the small animal specialty setting in North America

Veterinary Medicine and Science, 2019
Previous studies in human medicine have found that patients prefer their doctors to be more formally attired, and that this influences their trust and confidence in their physician.
Kathryn A. Robb, Tracey A. Rossi, Colleen Tansey, Gabrielle C. Hybki, Lisa A. Murphy, Reid K. Nakamura, Dillon Y. Chen   +6 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source