Results 71 to 80 of about 12,389,112 (241)

The role of human behaviour change in companion animal management: A case study of Praia de Faro, Portugal

Human-Animal Interactions
Humane dog and cat population management has relied on Trap, Neuter, Release (TNR) projects in an attempt to control or reduce free-roaming populations and improve the welfare of dogs and cats.
Harry Eckman, Elly Hiby
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Re-imagining Animal-Assisted Human Services (AAHS): Developing Canada’s first voluntary National Standard of Canada (NSC) for AAHS

Human-Animal Interactions
Animal-Assisted Human Services (AAHS) is a variety of interdisciplinary practices, including assistance/service animals and Animal-Assisted Interventions such as Animal-Assisted Activities, Animal-Assisted Learning, and Animal-Assisted Therapy. The Human-
Joanne Moss
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Exploring the human-bearded dragon animal bond: A qualitative content analysis of Reddit posts

Human-Animal Interactions
The impact of companion animals on humans has been extensively investigated. Previous and current literature has overwhelmingly focused on traditional companion animals, such as cats and dogs.
Leana Lovell, Anna Chur-Hansen
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A methodological tool for characterizing the therapeutic acts of animal-assisted therapy

Human-Animal Interactions
Animal-assisted psychotherapy (AAT) has established itself as a unique therapeutic method that combines dynamic interactions between humans and animals to promote clients’ goals, while promoting the well-being of the animals. This study aimed to identify
Arni Zacks, Oran Nitsani
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Care of rescued patients in large animal veterinary medicine: Opportunities in a changing landscape

Human-Animal Interactions
The landscape of veterinary medicine in the United States has undergone significant change in the past several decades. Specific to large animal medicine is the increasing demand for veterinary care of patients that have been rescued, including formerly ...
Page Walker Buck, Elizabeth Arbittier, Sarah Colmer, Barbara Dallap Schaer, Daniela Luethy, JoAnn Slack   +5 more
doaj   +1 more source