Results 91 to 100 of about 603,662 (274)
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Human-computer interaction department, Hewlett-Packard Laboratories [PDF]
, 1989 N. Kendzierski
openalex +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
User Perception of Facebook App Data Access: A Comparison of Methods and Privacy Concerns
Future Internet, 2016 Users share vast amounts of personal information online, but are they fully aware of what information they are sharing and with whom? In this paper, we focused on Facebook apps and set out to understand how concerned users are about privacy and how well ...
Jennifer Golbeck +1 more
doaj +1 more source
Book review: READINGS IN HUMAN-COMPUTER INTERACTION: A MULTIDISCIPLINARY APPROACH ed. by Ronald M . Baecker & William A.S. Buxton (Morgan Kaufmann Publishers, Inc ., 1987) [PDF]
, 1989 Maxine S. Cohen
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Molecular Oncology, EarlyView.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
A compliant metastructure design with reconfigurability up to six degrees of freedom
Nature CommunicationsCompliant mechanisms with reconfigurable degrees of freedom are gaining attention in the development of kinesthetic haptic devices, robotic systems, and mechanical metamaterials.
Humphrey Yang +8 more
doaj +1 more source
Soliton interaction in a fiber ring laser [PDF]
arXiv, 2009 We have experimentally investigated the soliton interaction in a passively mode-locked fiber ring laser and revealed the existence of three types of strong soliton interaction: a global type of soliton interaction caused by the existence of unstable CW components; a local type of soliton interaction mediated through the radiative dispersive waves; and ...
arxiv
Neural networks and pattern recognition in human-computer interaction [PDF]
, 1993 Janet Finlay, Russell Beale
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