Results 81 to 90 of about 1,769,245 (251)

Computers that smile: Humor in the interface [PDF]

, 2002
It is certainly not the case that wen we consider research on the role of human characteristics in the user interface of computers that no attention has been paid to the role of humor.
Nijholt, A.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Adaptive Real-Time Translation Assistance Through Eye-Tracking

AI
This study introduces the Eye-tracking Translation Software (ETS), a system that leverages eye-tracking data and real-time translation to enhance reading flow for non-native language users in complex, technical texts.
Dimosthenis Minas, Eleanna Theodosiou, Konstantinos Roumpas, Michalis Xenos   +3 more
doaj   +1 more source

Predicting and improving the recognition of emotions [PDF]

, 2018
The technological world is moving towards more effective and friendly human computer interaction. A key factor of these emerging requirements is the ability of future systems to recognise human emotions, since emotional information is an important part ...
Hakim, Ayesha
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

How deep is your trust? A comparative user requirements’ analysis of automation in medical and mobility technologies

Humanities & Social Sciences Communications
In a changing world full of innovative technologies, trust and trust requirements are increasingly important for designing user-centred systems and ensuring their long-term implementation.
Sophia Hick, Hannah Biermann, Martina Ziefle   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Eye-to-eye or face-to-face? Face and head substitution for co-located augmented reality

Frontiers in Virtual Reality
In co-located extended reality (XR) experiences, headsets occlude their wearers’ facial expressions, impeding natural conversation. We introduce two techniques to mitigate this using off-the-shelf hardware: compositing a view of a personalized avatar ...
Peter Kullmann, Theresa Schell, Mario Botsch, Marc Erich Latoschik   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source