Results 161 to 170 of about 3,603,331 (295)

TCRLens: structure-aware equivariant graph learning for TCR-pMHC-I recognition and immunogenic epitope discovery. [PDF]

Bioinform Adv
Siriarchawatana P, Ingsriswang S, Kaewborisuth C, Jongkaewwattana A.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Structural basis for bat receptor recognition by SARS-CoV-2 and bat SARS2-like coronaviruses. [PDF]

Commun Biol
Hsueh FC, Shi K, Aihara H, Li F.
europepmc   +1 more source

Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)

, 2010
Sebastian Eustermann, Christoph Brockmann, Pawan Vinod Mehrotra, Ji‐Chun Yang, David Loakes, Stephen C. West, Ivan Ahel, David Neuhaus   +7 more
openalex   +2 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Structural basis of odorant recognition by a mammalian class II odorant receptor. [PDF]

Sci Adv
Gil M, Choi C, Kim M, Bae M, Lee H, Choi I, Im W, Choi HJ.   +7 more
europepmc   +1 more source

Human–Structure Interaction During Rhythmic Jumping on Rectangular Plates Subjected to Time-Dependent Base Excitation

Phablo Veríssimo Inácio Dias, Zenón J.G.N. Del Prado   +1 more
openalex   +1 more source

A simplified method to account for vertical human-structure interaction

, 2021
Katrien Van Nimmen, Aleksandar Pavić, Peter Van den Broeck   +2 more
openalex   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

RIMap-RISC: a transcriptome-wide database of structurally modeled human microRNA interactions. [PDF]

Genome Biol
Chasles S, Gaillard-Duchassin Z, Quenneville J, Lemaire M, Gagnon E, Major F.   +5 more
europepmc   +1 more source