Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Animal 'Ritual' Killing: from Remains to Meanings [PDF]
As humans, we interact with our environment and the other species inhabiting it in a variety of ways. Animals not only provide a source of sustenance, but a means for humans to express their social concepts through interaction.
Morris, James
core
Self-disseminating vaccines for emerging infectious diseases. [PDF]
Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases ...
Jarvis, MA, Murphy, AA, Redwood, AJ
core +2 more sources
Anthropomorphism in Human–Animal Interactions: A Pragmatist View [PDF]
This paper explores anthropomorphism in human-animal interactions from the theoretical perspectives of pragmatism and anthropology of human-animal communication. Its aim is to challenge the conception of anthropomorphism as the attribution/inference of human properties to a non-human animal - particularly as a special case of the theory of mind.
openaire +4 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Effect of previous handling experiences on responses of dairy calves to routine husbandry procedures [PDF]
The nature of human–animal interactions is an important factor contributing to animal welfare and productivity. Reducing stress during routine husbandry procedures is likely to improve animal welfare.
McLeay, Lance M. +5 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Effects of therapeutic horseback riding on post-traumatic stress disorder in military veterans
Background Large numbers of post-deployment U.S. veterans are diagnosed with post-traumatic stress disorder (PTSD) and/or traumatic brain injury (TBI), leading to an urgent need for effective interventions to reduce symptoms and increase veterans’ coping.
Rebecca A. Johnson +12 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Spectacular pehnomena and limits to rationality in genetic and cultural evolution [PDF]
In studies of both animal and human behaviour, game theory is used as a tool for understanding strategies that appear in interactions between individuals.
Arak, Anthony +3 more
core

