Results 101 to 110 of about 2,814,535 (299)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Correction to 'Late Pleistocene shell midden microstratigraphy indicates a complex history of human-environment interactions in the uplands of North Vietnam'. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2022
McAdams C   +7 more
europepmc   +1 more source

ARAMIS: Toward a Hybrid Approach for Human- Environment Interaction [PDF]

open access: yes, 2011
In this paper we describe ARAMIS a novel hybrid approach aiming to enhance the human smart-environment interaction. We define this approach as hybrid since it is the combination of three different dichotomies: wearable and pervasive computing paradigms, virtual and real worlds, optical and nonoptical sensing technologies.
Stefano Carrino   +3 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Waypoints on a Journey of Discovery: Mental Models in Human-Environment Interactions

open access: yesEcology and Society, 2012
Although the broad concept of mental models is gaining currency as a way to explore the link between how people think and interact with their world, this concept is limited by a theoretical and practical understanding of how it can be applied in the ...
Timothy Lynam   +10 more
doaj   +1 more source

Late Pleistocene shell midden microstratigraphy indicates a complex history of human-environment interactions in the uplands of North Vietnam. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2022
McAdams C   +7 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Quantifying human-environment interactions using videography in the context of infectious disease transmission

open access: yesGeospatial Health, 2018
Quantitative data on human-environment interactions are needed to fully understand infectious disease transmission processes and conduct accurate risk assessments.
Timothy R. Julian   +6 more
doaj   +1 more source

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