Results 81 to 90 of about 2,814,535 (299)

Collective Sensing: Integrating Geospatial Technologies to Understand Urban Systems—An Overview

Remote Sensing, 2011
Cities are complex systems composed of numerous interacting components that evolve over multiple spatio-temporal scales. Consequently, no single data source is sufficient to satisfy the information needs required to map, monitor, model, and ultimately ...
Geoffrey J. Hay, Thomas Blaschke, Bernd Resch, Qihao Weng   +3 more
doaj   +1 more source

What contributes to individual differences in brain structure? [PDF]

, 2014
Individual differences in adult human brain structure have been found to reveal a great deal of information about variability in behaviors, cognitive abilities and mental and physical health.
Alexander, Ashburner, Aydin, Baaré, Banissy, Bartley, Bezzola, Cappelletti, Charney, Chiang, den Braber, Draganski, Eckert, Emerson, Engvig, Gaser, Geoffroy, Gilmore, Grossman, Haukvik, Hayashi, Ho, Hulshoff Pol, Hänggi, Hölzel, Hölzel, Jenny Gu, Johansen-Berg, Kabat-Zinn, Kanai, Kanai, Kim, Knott, Knudsen, Krause, Lai, Lerch, Lewis, Loehlin, Machizawa, Maguire, May, McCarney, Mori, Nieuwenhuis, Plomin, Rudebeck, Ryota Kanai, Soto, Stein, Sullivan, Thomas, Thompson, Wetterstrand, Woollett, Wray, Yamahachi, Zilles   +57 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Landscape Structures and Human Evolutionary Ecology: space, scale and environmental patterning in Africa

Internet Archaeology, 2015
Palaeoanthropologists and early prehistorians work hard to reconstruct ancient human-environment relationships and their influences on our lineage's ecology, biology and behaviour.
Isabelle C. Winder
doaj   +1 more source

Networking Phylogeny for Indo-European and Austronesian Languages [PDF]

, 2009
Harnessing cognitive abilities of many individuals, a language evolves upon their mutual interactions establishing a persistent social environment to which language is closely attuned. Human history is encoded in the rich sets of linguistic data by means
Dimitri Volchenkov, Filippo Petroni, Maurizio Serva, Philippe Blanchard   +3 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Time-domain THz spectroscopy reveals coupled protein-hydration dielectric response in solutions of native and fibrils of human lyso-zyme

, 2017
Here we reveal details of the interaction between human lysozyme proteins, both native and fibrils, and their water environment by intense terahertz time domain spectroscopy.
Appadoo, Dominique R. T., Blanch, Ewan W., Davis, Jeffrey A., Novelli, Fabio, Pour, Saeideh Ostovar, Roozbeh, Ashkan, Tollerud, Jonathan   +6 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source