Results 41 to 50 of about 109,968,647 (310)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Full-Body IMU-Based Motion Dataset of Daily Tasks by Older and Younger Adults

Scientific Data
This dataset (named CeTI-Age-Kinematics) fills the gap in existing motion capture (MoCap) data by recording kinematics of full-body movements during daily tasks in an age-comparative sample with 32 participants in two groups: older adults (66–75 years ...
Loreen Pogrzeba, Evelyn Muschter, Simon Hanisch, Veronica Y. P. Wardhani, Thorsten Strufe, Frank H. P. Fitzek, Shu-Chen Li   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Cortical processes of multisensory plausibility modulation of vibrotactile perception in virtual environments in middled-aged and older adults

Scientific Reports
Digital technologies, such as virtual or augmented reality, can potentially support neurocognitive functions of the aging populations worldwide and complement existing intervention methods.
Kathleen Y. L. Kang, Robert Rosenkranz, Mehmet Ercan Altinsoy, Shu-Chen Li   +3 more
doaj   +1 more source

Immersive Virtual Reality Assessment in Multiple Sclerosis: Patient-Reported Experience and Correlates

Brain Sciences
Background: Immersive virtual reality (VR) has emerged as a promising tool for standardized, engaging assessment of motor and cognitive function in people with multiple sclerosis (pwMS).
Anikó Vágó, Anne Geßner, Maximilian Hartmann, Heidi Stölzer-Hutsch, Katrin Trentzsch, Dirk Schriefer, Tjalf Ziemssen   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

VTQA: behavioral data from studies on compression ratios in vibrotactile signal processing

BMC Research Notes
Objectives This dataset collection aims to facilitate research on the transmission of digitized vibrotactile signals over communication networks, emphasizing the importance of minimizing delay and bandwidth requirements while preserving perceptual ...
Evelyn Muschter, Lars Nockenberg, Shu-Chen Li, Eckehard Steinbach   +3 more
doaj   +1 more source

Human-Cyber-Physical Systems for Energy Internet—A Review

Energies, 2023
As the research of HCPS in EI is ongoing, an increasing number of problems should be addressed, such as the leading role or aid function definition of humans, the coordination of humans with cyber and physical equipment, the state awareness of ...
Junwei Cao, Jian Jin, Yangyang Ming, Chuang Sun, Xiping Zeng, Zhenzhen Jiao, Songpu Ai   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A kinematic dataset of locomotion with gait and sit-to-stand movements of young adults

Scientific Data
Kinematic data is a valuable source of movement information that provides insights into the health status, mental state, and motor skills of individuals.
Simon Hanisch, Loreen Pogrzeba, Evelyn Muschter, Shu-Chen Li, Thorsten Strufe   +4 more
doaj   +1 more source