Understanding Empathy Toward Dissimilar Others in Challenging Everyday Interactions. [PDF]
Watanabe R, Kuruma H.
europepmc +1 more source
Clinical and Chemical Studies in Human Lactation.--I, II, and III [PDF]
F. E. Hytten
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Policies and guidelines supporting the sustainability of human milk donation to milk banks in Switzerland: a document analysis. [PDF]
Kaech C+4 more
europepmc +1 more source
The Distribution of I131 Labeled Human Serum Albumin Introduced into Ascitic Fluid: Analysis of the Kinetics of a Three Compartment Catenary Transfer System in Man and Speculations on Possible sites of Degradation [PDF]
Solomon A. Berson, Rosalyn S. Yalow
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
CRL2<sup>LRRC41</sup>-Mediated DDX5 Ubiquitination Enhances Interaction with ELAVL1 Preventing NOG mRNA Degradation and Sustaining Proliferation and Migration of Human Spermatogonial Stem Cell-Like Cell Line. [PDF]
Jiang B+9 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source