Results 231 to 240 of about 31,267,735 (386)

RNA-Guided Human Genome Engineering via Cas9

open access: yesScience, 2013
P. Mali   +7 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

The right to science in sexual and reproductive health and the legal status of the human embryo. [PDF]

open access: yesSex Reprod Health Matters
Dyer S   +4 more
europepmc   +1 more source

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

open access: yesCell, 2007
Kazutoshi Takahashi   +6 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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