Results 261 to 270 of about 31,267,735 (386)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Nag op 'n kaal plein.

Tydskrif vir Letterkunde, 2018
Thys Human
doaj  

Models of Endocrine-Disrupting Effects: Human Placental Steroidogenesis. [PDF]

Basic Clin Pharmacol Toxicol
Mathiesen L, Sandal D, Hammer IEM, Styrishave B, Knudsen LE.   +4 more
europepmc   +1 more source

Evaluation of the Level of Properdin in Normal Adult Humans and in Certain Disease States

, 1958
Victor D. Newcomer, Earl G. McNall, Carlyn Halde, Edwin T. Wright, Thomas H. Sternberg   +4 more
openalex   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Does Humanness Matter? An Ethical Evaluation of Sharing Care Work with Social Robots. [PDF]

Sci Eng Ethics
Mihailov E, Wangmo T.
europepmc   +1 more source

Art. III.—Inoculating the Human System with Straw Fungi, to protect it against the Contagion of Measles; with some Additional Observations relating to the Influence of Fungoid Growth in producing Disease and in the Fermentation and Putrefaction of Organic Bodies. [PDF]

J H Salisbury
openalex   +1 more source

OBSERVATIONS DURING APNEA IN CONSCIOUS HUMAN SUBJECTS [PDF]

, 1957
L Rumble, MANUEL N. COOPER, Donald S. Bickers, JOHN K. SCHELLACK, EDWARD J. WAITS, Kenneth H. Hyatt   +5 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Try to Look Again: A Phenomenological Study of Recognising Humanness in People Living With Advanced Dementia. [PDF]

Scand J Caring Sci
Bøgmose J, Olivares Bøgeskov B, Dening T, Martinsen B.   +3 more
europepmc   +1 more source