Results 101 to 110 of about 3,663,081 (289)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Delayed rewards weaken human goal directed actions

open access: yesnpj Science of Learning
Goal-directed actions are sensitive to the causal association between actions and outcomes, as well as the value of those outcomes. Such sensitivity diminishes when actions become habitual.
Omar David Perez, Gonzalo P. Urcelay
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

An Efficient Bayesian Approach to Exploit the Context of Object-Action Interaction for Object Recognition

open access: yesSensors, 2016
This research features object recognition that exploits the context of object-action interaction to enhance the recognition performance. Since objects have specific usages, and human actions corresponding to these usages can be associated with these ...
Sungbaek Yoon, Hyunjin Park, Juneho Yi
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Smith´s analysis of human actions

open access: yesEthic@: an International Journal for Moral Philosophy, 2005
In this article, Adam Smith’s ethics are explored; it is demanded how tenable some of his conclusions are. § 1 is focused on Smith’s treatment of selfish and non-selfish acts.
Jasper Doomen
doaj  

Humanization and Action

open access: yesRevista Iberoamericana de Bioética, 2018
En este artículo se revisa el significado de la palabra humanizar y el fundamento de la humanización entendido como vulnerabilidad y dignidad. Se resumen los ámbitos clave para la humanización, como el político-económico, el de la justicia, las estructuras, el cultural y el de la relación interpersonal.
Jose Carlos Bermejo   +1 more
openaire   +3 more sources

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