Results 81 to 90 of about 3,649,021 (290)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
[Human care: purification action].
Este estudo tem origem numa disciplina de mestrado. O tema “banho”, como ato de cuidado, foi desenvolvido, inicialmente, na forma de movimentos. A estética do movimento corporal, ao som de música foi retratado graficamente, permitindo chegar aos construtos como: relação, contato físico, compartilhamento, prazer, satisfação, limpeza, reaproximação.
Ribeiro Brum, Jane Lilian +5 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Aquest projecte se centra en el procés de reconeixement i classificació de les accions que realitza una persona en un moment concret, també conegut com Human Activity Recognition. Per a realitzar el reconeixement d'activitat i pose s'ha fet ús d'un algorisme de pose estimation, el qual proporciona l'esquelet de la persona i és d'ajuda per a classificar
Picazos Carrillo, Jose Antonio +1 more
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
İBRAHİM EL-KÛRÂNÎ’NİN HÂDİS KUDRETİ TASAVVURU VE ABDÜLGANÎ EN-NABLUSÎ’NİN ELEŞTİRİLERİ
İbrâhim el-Kûrânî, kelâm ve tasavvuf geleneğinin XVII. yüzyıldaki önemli isimlerindendir. Kûrânî’nin kelâm, tasavvuf ve hadis gibi alanlarda telif ettiği risaleler, kendisi hayattayken İslam dünyasının farklı bölgelerinde yaşayan âlimlere ulaşmış ve ...
Şerife Nur Çelik
doaj
Accurate Hierarchical Human Actions Recognition From Kinect Skeleton Data
Human action recognition has become one of the most active research topics in natural human interaction and artificial intelligence, and has attracted much attention.
Benyue Su +3 more
doaj +1 more source
Anticipating Daily Intention using On-Wrist Motion Triggered Sensing
Anticipating human intention by observing one's actions has many applications. For instance, picking up a cellphone, then a charger (actions) implies that one wants to charge the cellphone (intention). By anticipating the intention, an intelligent system
Chan, Cheng-Sheng +4 more
core +1 more source

