Results 241 to 250 of about 6,313,750 (303)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Bioassessment of Macroinvertebrate Communities Influenced by Gradients of Human Activities. [PDF]

Insects
Li R, Li X, Yang R, Farooq M, Tian Z, Xu Y, Shao N, Liu S, Xiao W.   +8 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Spatiotemporal dynamics of grassland aboveground biomass in northern China and the alpine region: Impacts of climate change and human activities. [PDF]

PLoS One
Wang X, Zhu J, Pan P.
europepmc   +1 more source

A hybrid TCN-GRU model for classifying human activities using smartphone inertial signals. [PDF]

PLoS One
Raja Sekaran S, Pang YH, You LZ, Yin OS.
europepmc   +1 more source

Assessing the impact of human activities on ecosystem asset dynamics in the Yellow River Basin from 2001 to 2020. [PDF]

Sci Rep
Ming L, Wang Y, Liu G, Meng L, Chen X.
europepmc   +1 more source

Human activities reshape the spatial overlap between North Chinese leopard and its wild ungulate prey. [PDF]

Front Zool
Wang Y, Liu M, Xia F, Li S.
europepmc   +1 more source

Toward Concurrent Identification of Human Activities with a Single Unifying Neural Network Classification: First Step. [PDF]

Sensors (Basel)
Smith A, Azeem M, Odhiambo CO, Wright PJ, Diktas HE, Upton S, Martin CK, Froeliger B, Corbett CF, Valafar H.   +9 more
europepmc   +1 more source

Zoonotic Parasites and Their Association With Human Activities in Northern Tanzania: An Integrated Ecosystem Approach for One Health. [PDF]

J Parasitol Res
Ndossi BA, Mjingo EE, Park H, Lee D, Bia MM, Yang H, Seo S, Eom KS.   +7 more
europepmc   +1 more source

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FIBRINOLYTIC ACTIVATOR ACTIVITY IN HUMAN NEOPLASMS

Plastic and Reconstructive Surgery, 1978
The results of this study suggest that many malignant tumors contain low levels of fibrinolytic activator activity. Evidence is presented to suggest that this low activity may be due to the presence of an inhibitor of fibrinolysis. The presence or absence of measurable fibrinolytic activator activity, and/or inhibitor in neoplastic growths may enable ...
J D, Franklin, A S, Gervin, D G, Bowers, J B, Lynch   +3 more
openaire   +2 more sources