Results 61 to 70 of about 8,493,857 (289)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Joint segmentation of multivariate time series with hidden process regression for human activity recognition

open access: yes, 2013
The problem of human activity recognition is central for understanding and predicting the human behavior, in particular in a prospective of assistive services to humans, such as health monitoring, well being, security, etc.
Amirat, Yacine   +4 more
core   +4 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Methodological advances in encoding models of brain: Applying temporal response functions to magnetoencephalography for written text perception

open access: yesNeuroImage
Recent advancements in cognitive neuroscience have expanded the tools available to study language processing beyond traditional event-related potentials (ERPs), and introduced new methods, such as the Temporal Response Function (TRF).
Gurgen Soghoyan   +3 more
doaj   +1 more source

Capturing Regular Human Activity through a Learning Context Memory [PDF]

open access: yes, 2006
A learning context memory consisting of two main parts is presented. The first part performs lossy data compression, keeping the amount of stored data at a minimum by combining similar context attributes — the compression rate for the presented GPS ...
Mohr, Philipp H.   +2 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Decoding the influence of anticipatory states on visual perception in the presence of temporal distractors

open access: yesNature Communications, 2018
Anticipation helps to prioritise the processing of task-relevant sensory targets over irrelevant distractors. Here the authors analyse visual EEG responses and show that anticipation may do so by enhancing the neural representation of the target and by ...
Freek van Ede   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Competitive athletes’ psychological and emotional experiences of injury rehabilitation: a scoping review

open access: yesSystematic Reviews
Background Sporting injuries have a psychological impact on competitive athletes, though most research focusses on the time of injury and returning to play.
Hazel R. Jaekel   +4 more
doaj   +1 more source

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