Results 81 to 90 of about 3,553,896 (268)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Levelling-up summer: using summer holiday programs to support child health and wellbeing – a Delphi study

BMC Public Health
Background Children’s health behaviours tend to worsen during the summer holidays, with declines in physical activity, diet, sleep, and mental wellbeing. Structured summer holiday programs may help counter these trends, while also supporting families and
Emily Eglitis, Timothy Olds, Rosa Virgara, Amanda Machell, Mandy Richardson, Kylie Brannelly, Carol Maher   +6 more
doaj   +1 more source

A Plasminogen Activator in Spontaneously Active Human Blood.

Experimental Biology and Medicine, 1953
Summary1. Fibrinolytically active blood, as obtained from the living and dead human organism, contains a plasminogen activator. The amount of this activator exceeds many times that needed for the complete activation of the plasminogen present in human blood. 2.
openaire   +2 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Evaluation of the Early Years South Australia mobile application

BMC Public Health
Background Released in July 2023 by the Office for Early Child Development in South Australia (SA), the Early Years SA mobile app supports parents of children aged 0–5 years with features including health check reminders, developmental milestone ...
Ben Singh, Kate Walker, Joann Fildes, Jessica Morley, Kylie Dankiw, Ty Ferguson, Rachel Curtis, Jacinta Brinsley, Carol Maher   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

An interactive tool to personalise 24-hour activity, sitting and sleep prescription for optimal health outcomes

npj Digital Medicine
Personalised interventions which optimise the balance of physical activity (PA), sleep and sedentary behaviour (i.e., time use) in the 24-h day may be more effective than one-size-fits-all approaches.
Maddison L. Mellow, Tyman E. Stanford, Timothy Olds, Aaron Miatke, Ashleigh E. Smith, Dorothea Dumuid   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source