Results 91 to 100 of about 222,876 (256)

In vitro and in vivo tropism and biodistribution of recombinant simian adenovirus type 25

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Recombinant adenoviruses are widely used in the development of vaccines for a variety of infectious diseases. Despite numerous clinical studies, only a few types of human (types 5 and 26) and simian (isolate Y25) adenoviruses are currently ...
Irina V. Vavilova, Tatiana A. Ozharovskaia, Olga V. Zubkova, Olga Popova, Daria V. Voronina, Polina P. Goldovskaya, Denis I. Zrelkin, Alina Sh. Dzharullaeva, Inna V. Dolzhikova, Dmitry V. Shcheblyakov, Denis Yu. Logunov, Alexander L. Gintsburg   +11 more
doaj   +1 more source

Identification and Application of Neutralizing Epitopes of Human Adenovirus Type 55 Hexon Protein

Viruses, 2015
Human adenovirus type 55 (HAdV55) is a newly identified re-emergent acute respiratory disease (ARD) pathogen with a proposed recombination of hexon gene between HAdV11 and HAdV14 strains.
Xingui Tian, Qiang Ma, Zaixue Jiang, Junfeng Huang, Qian Liu, Xiaomei Lu, Qingming Luo, Rong Zhou   +7 more
doaj   +1 more source

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China

Military Medical Research, 2017
Background Recruit training sites are places with a high incidence of respiratory infectious diseases. Effective surveillance for acute respiratory infectious diseases in a recruit training site is an important way to prevent disease outbreaks.
Wei-Wei Chen, Wen Xu, Yang-Xin Xie, Yun-Hui Zhang, Dan Wu, Fu-Sheng Wang, Min Zhao   +6 more
doaj   +1 more source

Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]

, 2007
We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T, Kirn, D, Korn, WM, Reid, TR, Sze, D, Thorne, S   +5 more
core  

RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells [PDF]

, 2019
Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative phosphorylation predominately account for energy production in C-MSC ...
Jin, Yue, Kim, Il-man, Shen, Yan, Su, Xuan, Tang, Yaoliang, Weintraub, Neal L.   +5 more
core   +1 more source

Defective Virions in Human Adenovirus Type 12 [PDF]

Journal of Virology, 1971
Purified preparations of human adenovirus type 12 showed two bands when subjected to isopycnic centrifugation in a density gradient of cesium chloride. Their density difference was about 0.003 g/ml, suggesting a small difference in their deoxyribonucleic acid to protein ratio.
openaire   +2 more sources

Supplementary Materials and Methods from A Novel <i>CDC25B</i> Promoter–Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models

, 2023
Helga L. Weber, Manuel Gidekel, Santiago Werbajh, Edgardo Salvatierra, Cecilia Rotondaro, Leonardo Sganga, Gabriela Acosta Haab, David T. Curiel, Eduardo G. Cafferata, Osvaldo L. Podhajcer   +9 more
openalex   +1 more source

Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice

Journal of Biomedical Science, 2009
Human interleukin-15 (hIL15) has anti-tumor activities, but it is not convenient for tumor treatment because of its short half-life. A gene therapy for mouse lung cancer using an adenovirus vector expressing IL15 has been reported.
Hung Yu-Ting, Hu Sheng-Chuan, Yu Yung-Luen, Harn Horng-Jyh, Yiang Giou-Teng, Hsieh Chia-Jung, Lin Shinn-Zong, Wei Chyou-Wei   +7 more
doaj   +1 more source

Evaluation of biodistribution and safety of adenovirus vector containing MDR1 in mice

Journal of Experimental & Clinical Cancer Research, 2010
Background The aim of this study is to examine the safety and distribution of Ad-EGFP-MDR1, an adenovirus encoding human multidurg resistance gene (human MDR1), in the mice colon carcinoma model.
Luo Qing, Zheng GaiHuan, Zhu Jin, Su YuXi, Liu Wei, Zhao ZhenZhen, Jin XianQing   +6 more
doaj   +1 more source