Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund +92 more
core +1 more source
A Human Adenovirus Enhances Preadipocyte Differentiation [PDF]
AbstractObjectives: Adenovirus 36 (Ad‐36) has been shown to increase adiposity in experimentally infected chickens, mice, and marmosets (nonhuman primates). Neutralizing antibodies to Ad‐36 are associated with obesity in humans. The metabolic and molecular mechanisms responsible for Ad‐36‐induced adipogenesis are unknown.
Sharada D, Vangipuram +4 more
openaire +2 more sources
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells [PDF]
Background: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence.
Beier, Dagmar +9 more
core +1 more source
Adenovirus 38: a New Human Adenovirus Species of Subgenus D
From the stool of a Dutch girl, a new virus (LJ) was isolated that by morphological, biological, and immunological criteria was a human adenovirus. Because of its hemagglutinating activity for rat and human red blood cells and its DNA restriction enzyme pattern, the virus was classified as a member of subgenus D. It was distinct in neutralization tests
de Jong, JC +6 more
openaire +3 more sources
Human adenovirus (HAdV) is the primary cause of acute conjunctivitis. To improve our understanding of the etiology of adenoviral conjunctivitis, ocular samples were collected from 160 conjunctivitis cases in the Shanxi province of northern China between ...
Jitao Wang +12 more
doaj +1 more source
Human Adenovirus Modulates Surfactant Phospholipid Trafficking [PDF]
Surfactant, highly enriched with phosphatidylcholine (PC), is secreted into the airspace by a classic apical secretory route, thereby maintaining lung stability. Herein, we show that adenoviral infection decreases surfactant PC in lungs by inhibiting its apical secretion and redirecting its export in alveolar cells by a basolateral route. These effects
Olga L, Miakotina +4 more
openaire +2 more sources
Adenovirus replication and host innate response in primary human airway epithelial cells
Background: Adenovirus infections are very common in children and sometimes fatal. Immune responses and hypercytokinemia are related to disease severity in patients with adenovirus infection.
Tzu-I Yang +7 more
doaj +1 more source
Human adenovirus-5 (hAd5) is an important gene delivery vector, which has been widely used in various fields of biomedicine, such as gene therapy, cancer therapy, and vaccine development.
Wenbo Xie +4 more
doaj +1 more source
Epidemiology of human adenovirus and molecular characterization of human adenovirus 55 in China, 2009–2012 [PDF]
Background Human adenovirus 55 ( HA dV‐55) has caused recent outbreaks of acute respiratory disease ( ARD ) among adults and military trainees. The active surveillance for HA
Lu, Q.-B +7 more
openaire +2 more sources
Incidence of viral respiratory infections in a prospective cohort of outpatient and hospitalized children aged ≤5 years and its associated cost in Buenos Aires, Argentina [PDF]
Background: Although information about the incidence of viral respiratory illnesses and their associated cost can help health officials explore the value of interventions, data are limited from middle-income countries.
Azziz Baumgartner, Eduardo +6 more
core +1 more source

