The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song +7 more
wiley +1 more source
Markedly enhanced intratumoral spread and antitumor effect of oncolytic adenovirus expressing decorin [PDF]
, 2008 With the aim of improving viral distribution and tumor penetration, we have engineered decorin expressing replication-incompetent (dl-LacZ-DCNG) and -competent (Ad-[DELTA]E1B-DCNG) adenoviruses.
Joo-Hang Kim +7 more
core +1 more source
Human adenoviruses in paediatric patients with respiratory tract infections in Beijing, China. [PDF]
Virol J, 2021 Huang Y +7 more
europepmc +1 more source
Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng +8 more
wiley +1 more source
Heparan Sulfate Is a Cellular Receptor for Enteric Human Adenoviruses. [PDF]
Viruses, 2021 Rajan A +7 more
europepmc +1 more source
Viral diversity influences T-cell responses to enteric human adenoviruses F40 and F41. [PDF]
Virus EvolCraven HM +7 more
europepmc +2 more sources
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
Molecular Carcinogenesis, EarlyView.ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
Whole genome-based surveillance for human adenovirus-related diseases in Kobe City, Japan, 2018–2022
BMC Research NotesBackground Human adenoviruses (HAdVs) cause various diseases, and they frequently undergo recombination. As adenoviruses are susceptible to recombination, whole-genome sequencing and analysis are essential approaches to understanding viral properties. In
Yoshihiko Tanimoto +6 more
doaj +1 more source
Development and Application of a Fast Method to Acquire the Accurate Whole-Genome Sequences of Human Adenoviruses. [PDF]
Front Microbiol, 2021 Zhao S +8 more
europepmc +1 more source