Results 261 to 270 of about 2,152,983 (311)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Pregnancy associated plasma protein-A2 (PAPP-A2) and stanniocalcin-2 (STC2) but not PAPP-A are associated with circulating total IGF-1 in a human adult population. [PDF]

Sci Rep
Nimptsch K, Aydin EE, Chavarria RFR, Janke J, Poy MN, Oxvig C, Steinbrecher A, Pischon T.   +7 more
europepmc   +1 more source

Basic Fibroblast Growth Factor Induces Matrix Metalloproteinase-13 via ERK MAP Kinase-Altered Phosphorylation and Sumoylation of Elk-1 in Human Adult Articular Chondrocytes [Expression of Concern]. [PDF]

Open Access Rheumatol
europepmc   +1 more source

Neurogenesis in adult human

NeuroReport, 1996
This report describes neurogenesis in the adult human olfactory epithelium in vitro. Olfactory epithelium was collected at autopsy and by biopsy, and grown in serum-free medium. Basic fibroblast growth factor induced the differentiation of bipolar cells which were immunopositive for several neuronal proteins but not glial proteins.
Murrell, Wayne, Bushell, Gillian R., Livesey, Jonathon, McGrath, John, MacDonald, Kelli P.A., Bates, Paul R., Mackay Sim, Alan   +6 more
openaire   +6 more sources

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Evidence of adult neurogenesis in non-human primates and human

Cell and Tissue Research, 2014
Adult neurogenesis in rodents has been extensively studied. Here, we briefly summarize the studies of adult neurogenesis based on non-human primate brains and human postmortem brain samples in recent decades. The differences between rodent, primate and human neurogenesis are discussed.
Ti-Fei Yuan, Fei Ding, OSCAR Arias-Carrión   +2 more
exaly   +3 more sources

TOXOPLASMOSIS IN THE HUMAN ADULT

Archives of Internal Medicine, 1952
HUMAN toxoplasmosis has been recognized with increasing frequency since the first description of the disease by Janku 1 in 1923 and the demonstration by Wolf, Cowen, and Paige 2 of Toxoplasma as a cause of congenital encephalomyelitis with hydrocephalus, intracerebral calcifications, microcephaly, chorioretinitis, and microphthalmos.
E H, KASS, S B, ANDRUS, R D, ADAMS, F C, TURNER, H A, FELDMAN   +4 more
openaire   +2 more sources

The human adult cardiomyocyte phenotype

Cardiovascular Research, 2003
Determination of the phenotype of adult human atrial and ventricular myocytes based on gene expression and morphology.Atrial and ventricular cardiomyocytes were obtained from patients undergoing cardiac surgery using a modified isolation procedure. Myocytes were isolated and cultured with or without serum.
Bird, SD, Doevendans, PA, van Rooijen, MA, de la Riviere, AB, Hassink, RJ, Passier, R, Mummery, CL   +6 more
openaire   +3 more sources

Discomalleolar Ligament in the Adult Human

CRANIO®, 1986
AbstractThe ligamentous structures connecting the temporomandibular joint region and the middle ear were investigated in adult cadavers by the superior approach through the middle cranial fossa. As a result, two ligaments—the continuation of the sphenomandibular ligament with the malleus and the discomalleolar ligament—were present. They passed through
E, Komori, M, Sugisaki, H, Tanabe, S, Katoh   +3 more
openaire   +2 more sources