Results 41 to 50 of about 2,152,983 (311)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]

, 2010
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N., Maizels, R M, Burchmore, R., Y. HARCUS, Mduluza, T., R. M. MAIZELS, Harcus, Y, Turner, C.M.R., R. BURCHMORE, C. M. TURNER, Mutapi, F, Midzi, N, Mutapi, F., Maizels, R.M., Turner, C M, Maizels, RM, N. MIDZI, Harcus, Y., Bourke, C., F. MUTAPI, T. MDULUZA, Turner, CM, Maizels, R. M., Bourke, C, Turner, C. M., Mduluza, T, Burchmore, R.J.S., Burchmore, R, C. BOURKE   +28 more
core   +1 more source

Gliosarcoma: A Reappraisal of Neuroradiological, Surgical, Morphological, and Radiotherapeutic Characteristics of a Cohort From South Italy Single-Center

Analytical Cellular Pathology
Gliosarcoma (GS) is a rare and aggressive variant of glioblastoma multiforme (GBM), characterized by a biphasic histopathological pattern featuring both glial and mesenchymal components.
Ida Rizzuto, Antonio Ieni, Sarah Caroline Scarcella, Valentina Sciacca, Vincenzo Fiorentino, Claudio Napoli, Maurizio Martini, Antonino Germanò, Francesca Granata, Stefano Pergolizzi, Giovanni Tuccari   +10 more
doaj   +1 more source

Adult Reye-like syndrome associated with serologic evidence of acute parvovirus B19 infection

Brazilian Journal of Infectious Diseases
Reye's syndrome is an infrequently diagnosed medical condition affecting mainly children. The etiology, epidemiology and natural history of Reye's syndrome have been cloudily written in footnotes of medical books and exotic papers since the initial ...
Paulo Sérgio Gonçalves da Costa, Geyza Machado Ribeiro, Thiago Cardoso Vale, Thaís Gomes Casali, Flávio José Barbosa Leite   +4 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation

, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632), Jennifer Scott, Heather Thomson, Xiaoli Chen, Lotery, Andrew J., Xiaoli Chen (102563), Cooke, J.J., Scott, Jennifer A., Andrew Lotery, Heather Thomson (637631), Thomson, Heather, Jessica Cooke, Parwez Hossain, Jennifer Scott (637633), Chen, Xiaoli, Hossain, Parwez, Andrew Lotery (637635), Parwez Hossain (637634)   +17 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Adult Learning on the Edge of a Precipice: an ecology of living and learning [PDF]

, 2022
Alan Bainbridge - ORCID: 0000-0001-7783-7747 https://orcid.org/0000-0001-7783-7747This article considers adult learning from a ‘long-life’ perspective. Stepping out of con-temporary frames that position adult learning as ‘life-long’ or even ‘life-wide’
Bainbridge, Alan
core   +1 more source

Planned posterior assisted levitation in severe subluxated cataract: Surgical technique and clinical results

Indian Journal of Ophthalmology, 2012
We report the surgical technique and outcome of planned posterior assisted levitation (P-PAL) in four cases of subluxated cataract. P-PAL was planned as the preferred approach in all cases.
Tova Lifshitz, Jaime Levy, Assaf Kratz, Nadav Belfair, Erez Tsumi   +4 more
doaj   +1 more source