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Conflict and human African trypanosomiasis
Social Science & Medicine, 2011Human African Trypanosomiasis (HAT) has reemerged in sub-Saharan Africa as a disease of major public health importance. The success of HAT elimination in sub-Saharan Africa is subject to the feasibility of controlling, eliminating, or mitigating the determinants of incidence in affected countries.
Lea Berrang-Ford +2 more
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Human African trypanosomiasis: MRI
Neuroradiology, 1997We report a case of human African trypanosomiasis caused by Trypanosoma brucei rhodesiense. After the febrile period of parasite dissemination, the patient had meningeal involvement but normal CT. MRI showed the appearances of meningitis. After two periods of arsenical treatment, a severe encephalopathy occurred suggesting post-therapeutic reactive ...
C. Brosset +5 more
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Human African trypanosomiasis & heart
Expert Review of Cardiovascular Therapy, 2020Human African Trypanosomiasis is a neglected tropical disease resulting from the infection with the parasite Trypanosoma brucei. Neurological compromise often dominates, and the impact of cardiovascular involvement has not been fully investigated. Recently, publications indicate that cardiovascular compromise is more frequent than previously thought ...
Hector Isaac Alejandro Ortiz +8 more
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Infectious Disease Clinics of North America, 2019
Control efforts have considerably reduced the prevalence of human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in West/Central Africa and to Trypanosoma brucei rhodesiense in East Africa. Management of T brucei gambiense HAT has recently improved, with new antibody-based rapid diagnostic tests suited for mass screening and clinical
Jan Clerinx, Emmanuel Bottieau
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Control efforts have considerably reduced the prevalence of human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in West/Central Africa and to Trypanosoma brucei rhodesiense in East Africa. Management of T brucei gambiense HAT has recently improved, with new antibody-based rapid diagnostic tests suited for mass screening and clinical
Jan Clerinx, Emmanuel Bottieau
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Chemotherapy of Human African Trypanosomiasis
Current Pharmaceutical Design, 2002Human African trypanosomiasis or sleeping sickness is resurgent [1,2]. The disease is caused by subspecies of the parasitic haemoflagellate, Trypanosoma brucei. Infection starts with the bite of an infected tsetse fly (Glossina spp.). Parasites move from the site of infection to the draining lymphatic vessels and blood stream. The parasites proliferate
Bertin Enanga +3 more
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The Lancet
Human African trypanosomiasis or sleeping sickness is caused by infection with Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense parasites, which are transmitted by tsetse flies in sub-Saharan Africa. Control of human African trypanosomiasis is based on case detection, treatment, and vector control.
Veerle, Lejon +2 more
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Human African trypanosomiasis or sleeping sickness is caused by infection with Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense parasites, which are transmitted by tsetse flies in sub-Saharan Africa. Control of human African trypanosomiasis is based on case detection, treatment, and vector control.
Veerle, Lejon +2 more
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2009
Human African trypanosomiasis (HAT) is caused by two subspecies of trypanosomes, Trypanosoma brucei gambiense and T.b. rhodesiense. Clinically, the disease is characterized by an early stage during which patients report non-specifi c symptoms such as fever and malaise, and trypanosomes are found in the blood or in lymph node aspirates.
Honore Meda, Jacques Pépin
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Human African trypanosomiasis (HAT) is caused by two subspecies of trypanosomes, Trypanosoma brucei gambiense and T.b. rhodesiense. Clinically, the disease is characterized by an early stage during which patients report non-specifi c symptoms such as fever and malaise, and trypanosomes are found in the blood or in lymph node aspirates.
Honore Meda, Jacques Pépin
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Human and animal African trypanosomiasis.
2015Abstract This chapter describes the evolution of a One Health approach - the Stamp Out Sleeping Sickness (SOS) campaign - that has been key to the sustainable control of Trypanosoma brucei rhodesiense in humans and animals in Uganda.
Susan C. Welburn +6 more
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Drug Resistance in Human African Trypanosomiasis
Future Microbiology, 2011Human African trypanosomiasis or 'sleeping sickness' is a neglected tropical disease caused by the parasite Trypanosoma brucei. A decade of intense international cooperation has brought the incidence to fewer than 10,000 reported cases per annum with anti-trypanosomal drugs, particularly against stage 2 disease where the CNS is involved, being central ...
Enock Matovu +4 more
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Recent developments in human African trypanosomiasis
Current Opinion in Infectious Diseases, 2002Sleeping sickness has re-emerged as a serious problem in sub-Saharan Africa, with an estimated 100000 deaths each year. South Sudan, the Democratic Republic of Congo and Angola have experienced serious epidemics of the Gambian form of the disease.
Susan C. Welburn, Martin Odiit
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