Results 141 to 150 of about 12,614,860 (303)

RETRACTION: Multimodal Data Fusion Framework for Early Prediction of Autism Spectrum Disorder

Human Behavior and Emerging Technologies
Human Behavior and Emerging Technologies
doaj   +1 more source

DIURNAL RHYTHM OF LEARNING AND MEMORY REGULATED BY SCOP IN MICE AND NONHUMAN PRIMATES

IBRO Neuroscience Reports, 2023
Kimiko Shimizu, Ken-Ichi Inoue, Takao Oishi, Hiroo Imai, Masahiko Takada, Yoshitaka Fukada   +5 more
doaj   +1 more source

Automatic value learning results in counterproductive human behavior. [PDF]

Nat Commun
Ben-Artzi I, Pereg M, Luria R, Moran R, Shahar N.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Human behavior alignment to improve the robustness of deep neural networks. [PDF]

Front Artif Intell
Anand B, Krithivasan S.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Diversifying Methods in Evolutionary Anthropology: Autophotography as a Tool for Quasi-Naturalistic Observation of Human Behavior. [PDF]

Evol Anthropol
Emmott EH, Morita M.
europepmc   +1 more source

The value of intersectionality for genomic research on human behavior. [PDF]

Genet Med, 2023
Matthews LJ, Martschenko DO, Sabatello M.   +2 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Measuring human behavior through controlled perturbations: a framework for reconstructing behavioral systems. [PDF]

Front Psychol
Cipresso P.
europepmc   +1 more source