Results 171 to 180 of about 12,614,860 (303)

Advances in deep reinforcement learning enable better predictions of human behavior in time-continuous tasks. [PDF]

PLoS One
Haberland S, Ruge H, Frimmel H.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Awe is characterized as an ambivalent affect in the human behavior and cortex. [PDF]

Commun Psychol
Lee J, Han DD, Oh SY, Cha J.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

DISCOVER: a Data-driven Interactive System for Comprehensive Observation, Visualization, and ExploRation of human behavior. [PDF]

Front Digit Health
Hallmen T, Schiller D, Vehlen A, Eberhardt S, Baur T, Withanage Don D, Lutz W, André E.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Characterizing population-level changes in human behavior during the COVID-19 pandemic in the United States. [PDF]

Proc Natl Acad Sci U S A
Urmi T, Pant B, Dewey G, Quintana-Mathe A, Lang I, Druckman J, Ognyanova K, Baum M, Perlis R, Riedl C, Lazer D, Santillana M.   +11 more
europepmc   +1 more source

Human behavior recognition based on sparse transformer with channel attention mechanism. [PDF]

Front Physiol, 2023
Cao K, Wang M.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A human behavior-based model for respiratory infectious diseases prediction. [PDF]

Front Public Health
Ma Z, Zhu M, Zhi C, Zhang H, Li M, Zhang N, Ma H.   +6 more
europepmc   +1 more source