Results 241 to 250 of about 5,187,370 (343)

Research on Multi-Scale Spatio-Temporal Graph Convolutional Human Behavior Recognition Method Incorporating Multi-Granularity Features. [PDF]

Sensors (Basel)
Wang Y, Song T, Yang Y, Hong Z.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Neural mechanisms of response inhibition and impulsivity in 22q11.2 deletion carriers and idiopathic attention deficit hyperactivity disorder

NeuroImage: Clinical, 2015
C.A. Montojo, E. Congdon, L. Hwang, M. Jalbrzikowski, L. Kushan, T.K. Vesagas, R.K. Jonas, J. Ventura, R.M. Bilder, C.E. Bearden   +9 more
doaj   +1 more source

Impact of nighttime human behavior on exposure to malaria vectors and effectiveness of using long-lasting insecticidal nets in the Ethiopian lowlands and highlands. [PDF]

Parasit Vectors
Esayas E, Gowelo S, Assefa M, Vajda EA, Thomsen E, Getachew A, Ashine T, Mekonnen G, Ntuku H, Bennett A, Golassa L, Lobo NF, Gadisa E.   +12 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

X- vs. Y-chromosome influences on human behavior: a deep phenotypic comparison of psychopathology in XXY and XYY syndromes. [PDF]

J Neurodev Disord
Schaffer L, Rau S, Larsen IG, Clasen L, Warling A, Whitman ET, Nadig A, McDermott C, Xenophontos A, Wilson K, Blumenthal J, Torres E, Raznahan A.   +12 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Shape of Relations to Come: Multidimensional Analyses of Complex Human Behavior. [PDF]

Psychol Rec
Mason L, Andrews A, Otero M, James-Kelly K.   +3 more
europepmc   +1 more source

The contributions of global and local object landmarks in Human Wayfinding behavior

, 2010
Wen‐Jing Lin, Tai‐Yin Huang, Li‐Wei Ko, Chin‐Teng Lin, Daisy L. Hung, Erik C. Chang   +5 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source