Results 141 to 150 of about 9,633,208 (257)

Influence of functional gene polymorphisms on human behaviour: the case of CCR5. [PDF]

J Psychiatry Neurosci, 2021
Albert PR.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Modelling the Role of Human Behaviour in Ebola Virus Disease (EVD) Transmission Dynamics. [PDF]

Comput Math Methods Med, 2022
Djiomba Njankou SD, Nyabadza F.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Human behaviour and climate-linked fluctuations in the rainforests of West-Central Africa. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2022
Orijemie EA.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Decoding of Human Behaviour and Personality. [PDF]

Ann Neurosci
Kamble P, Magan D, Daulatabad V, Yadav RK, Bhargav H, Pandey S.   +5 more
europepmc   +1 more source

Human behaviour, NPI and mobility reduction effects on COVID-19 transmission in different countries of the world. [PDF]

BMC Public Health, 2022
Mohammadi Z, Cojocaru MG, Thommes EW.
europepmc   +1 more source

The Journey or the Destination: The Impact of Transparency and Goal Attainment on Trust in Human-Robot Teams

As robots gain autonomy, human-robot task delegation can become more goal-oriented; specifying what to do rather than how. This can lead to unexpected robot behaviour.
Boogaard, J. van den, Turjaka, V., Kerstholt, J.H., Kox, E.S.   +3 more
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