Results 151 to 160 of about 9,633,208 (257)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Bridging the gap between human behaviour and animal welfare: A study on human behaviour change and body condition scoring of suckler cows. [PDF]

Anim Welf
Jessiman L, Naydani CJ, Rutherford KM, Turner SP.   +3 more
europepmc   +1 more source

Human behaviour should be recorded in (dis)comfort research. [PDF]

Work, 2021
Smulders M, Vink P.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Projecting the future spread of yellow fever vectors and implications for epidemic risk: a scoping review of climate change and human behaviour. [PDF]

BMJ Open
Parreiras-Gonçalves A, Failloux AB, Jelinek T, LaBeaud AD, Langevin E, Ooi EE, Thollot Y, Tomori O, Vasilakis N, Lowe R, Colón-González FJ.   +10 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Does the internet help governments contain the COVID-19 pandemic? Multi-country evidence from online human behaviour. [PDF]

Gov Inf Q, 2022
Zhang Q, Phang CW, Zhang C.
europepmc   +1 more source

BRIDGING THE FIELDS OF INNOVATIVE BEHAVIOUR AND HUMAN RESOURCE MANAGEMENT: A SYSTEMATIC REVIEW AND FUTURE RESEARCH DIRECTIONS

, 2014
Research has underlined the importance of Individual Innovative Behaviour or Innovative Work Behaviour (IWB) for firms’ success and long term survival.
TINTORRI S., Tintorri, Sara, BONESSO, Sara, BONESSO S.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Linking Anopheles bionomics and human behaviour in the Lao PDR. [PDF]

Malar J
Marcombe S, Maithaviphet S, Reyburn R, Kunlaya K, Silavong K, Hongvanthong B, Vanisaveth V, Sengsavath V, Banouvong V, Chindavongsa K, Khamlome B, Vajda ÉA, Thomsen E, Finn T, Lobo NF, Shortus M.   +15 more
europepmc   +1 more source