Results 151 to 160 of about 11,854,055 (309)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Bridging the gap between human behaviour and animal welfare: A study on human behaviour change and body condition scoring of suckler cows. [PDF]

Anim Welf
Jessiman L, Naydani CJ, Rutherford KM, Turner SP.   +3 more
europepmc   +1 more source

Does the internet help governments contain the COVID-19 pandemic? Multi-country evidence from online human behaviour. [PDF]

Gov Inf Q, 2022
Zhang Q, Phang CW, Zhang C.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Linking Anopheles bionomics and human behaviour in the Lao PDR. [PDF]

Malar J
Marcombe S, Maithaviphet S, Reyburn R, Kunlaya K, Silavong K, Hongvanthong B, Vanisaveth V, Sengsavath V, Banouvong V, Chindavongsa K, Khamlome B, Vajda ÉA, Thomsen E, Finn T, Lobo NF, Shortus M.   +15 more
europepmc   +1 more source

Using machine learning to extract information and predict outcomes from reports of randomised trials of smoking cessation interventions in the Human Behaviour-Change Project. [PDF]

Wellcome Open Res, 2023
West R, Bonin F, Thomas J, Wright AJ, Mac Aonghusa P, Gleize M, Hou Y, O'Mara-Eves A, Hastings J, Johnston M, Michie S.   +10 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keeping Cats Safe at Home (KCSAH): Lessons Learned from a Human Behaviour Change Campaign to Reduce the Impacts of Free-Roaming Domestic Cats. [PDF]

Animals (Basel)
Ma GC, Gates MC, Littlewood KE, Zito S, Kennedy BPA.   +4 more
europepmc   +1 more source

Research on the Training and Management of Industrializing Workers in Prefabricated Building with Machine Vision and Human Behaviour Modelling Based on Industry 4.0 Era. [PDF]

Comput Intell Neurosci, 2022
Wang J, Song Y, Yuan C, Guo F, Huangfu Y, Liu Y.   +5 more
europepmc   +1 more source