Optical Screening and Classification of Drug Binding to Proteins in Human Blood Serum. [PDF]
Anal Chem, 2023 Rutherford SH +6 more
europepmc +1 more source
Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
, 2017 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan +6 more
core +3 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Stratification of hypertension and SARS-CoV-2 infection by quantitative NMR spectroscopy of human blood serum. [PDF]
Commun Med (Lond), 2023 Kazenwadel J +8 more
europepmc +1 more source
Longitudinal determination of serum placental protein 13 during development of preeclampsia [PDF]
, 2008 Objective: To determine maternal serum placental protein 13 (PP13) in normal pregnancy and preeclampsia. Methods: A prospective, longitudinal study with 41 normal pregnant women, 18 cases with preterm delivery or cervix insufficiency and 4 with ...
Bartz, Clemens +5 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
A Fluorescent Cage for Supramolecular Sensing of 3-Nitrotyrosine in Human Blood Serum. [PDF]
Angew Chem Int Ed Engl, 2022 Pérez-Márquez LA +4 more
europepmc +1 more source
Cellular uptake of soy-derived phytoestrogens in vitro and in human whole blood [PDF]
, 2008 Epidemiological studies comparing typical Western and traditional Eastern lifestyles indicate that dietary intake of soyderived phytoestrogens, including genistein, daidzein, and equol, may have significant health protective effects on hormone-dependent ...
Bracke, Marc +4 more
core
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Blood Coagulation Favors Anti-Inflammatory Immune Responses in Whole Blood
Hematology ReportsBackground: We studied the effects of human blood coagulation on antioxidant activity and the cellular secretion of immunoregulatory molecules in vitro.
Victor I. Seledtsov +4 more
doaj +1 more source