Results 91 to 100 of about 2,100,730 (306)

Novel screening methods for the detection of Yersinia enterocolitica in infected blood used for transfusion : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

open access: yes, 2000
Between 1991-1996, 8 patients experienced rare life-threatening reactions that followed the transfusion of blood infected with Yersinia enterocolitica.
Kendrick, Christopher John
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS—evaluation of whole blood, plasma, and serum as sample matrices

open access: yesArthritis Research & Therapy, 2020
Background Hydroxychloroquine (HCQ) is the standard of care in the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and other inflammatory rheumatic diseases and potentially for the treatment in COVID-19 patients. Determination
Henrik Carlsson   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Effect of giardia on some biochemical variables in human blood serum

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2005
The alteration in serum glutamic-oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), alkaline phosphotase (ALP) and total protein during giardiasis were studied.
Al-jebory K. Abdul-Hussien
doaj   +1 more source

Zinc and Copper Levels in Patients with Primary Hypertension and Normotension [PDF]

open access: yes, 2015
One of the causes of primary hypertension is an exposure to free radicals. The formation of free radicals in the body can be prevented by taking antioxidants. Zinc and copper are cofactors of endogenous antioxidant enzyme superoxide dismutase. This study
Adriani, M. (Merryana)   +2 more
core  

Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]

open access: yes, 2016
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J.   +7 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Resveratrol-Loaded Albumin Nanoparticles with Prolonged Blood Circulation and Improved Biocompatibility for Highly Effective Targeted Pancreatic Tumor Therapy

open access: yesNanoscale Research Letters, 2017
Human serum albumin (HSA) is an intrinsic protein and important carrier that transports endogenous as well as exogenous substances across cell membranes.
Tao Geng   +4 more
doaj   +1 more source

Vitamin B12, in Human Blood and Serum

open access: yesClinical Chemistry, 1960
Abstract A comparison of microbiologic assays for vitamin B12 in whole blood or serum was carried out with four B12-requiring microorganisms, Escherichia coli 113-3, Lactobacillus leichmannii ATCC No. 7839, Euglena gracilis, strain Z, and Ochromonas malhamensis. B12 values in whole blood and serum for normal subjects are given. The value
Harry Sobotka   +3 more
openaire   +1 more source

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