Results 81 to 90 of about 2,496,590 (268)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Computer Vision Based Recognition of Interactions between Human Body and Object [PDF]
, 2003 Masumi Kobana, Jun Ohya
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
RADIATION OF HEAT FROM THE HUMAN BODY: A STATEMENT RELATIVE TO THE CRITIQUE OF J. D. HARDY [PDF]
, 1934 H. Bohnenkamp
openalex +1 more source
IMPACT OF TENNIS ON THE HUMAN BODY: SCIENTIFIC LITERATURE ANALYSIS OF DATA
, 2023 Azamatov A.I, Alimova M.B
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Students’ conceptions about energy and the human body [PDF]
Science Education International, 2010 Students’ understanding of energy has been primarily within the domain ofphysics. This study sought to examine students’ understanding of conceptsrelating to energy and the human body using pencil and paperquestionnaires administered to 610 students in ...
David F Treagust, Michael Mann
doaj
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Over or Under? Mental Representations and the Paradox of Body Size Estimation
Frontiers in Psychology, 2021 Kevin R. Brooks +5 more
doaj +1 more source