Results 101 to 110 of about 412,962 (313)
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Gynecology and Obstetrics Clinical MedicinePurpose Systemic inflammation has been increasingly implicated in the pathogenesis of polycystic ovary syndrome (PCOS), but the causal nature and direction of this relationship remain uncertain.
Qun Lu +3 more
doaj +1 more source
America's Human Capital Paradox [PDF]
SSRN Electronic Journal, 2012 It is widely recognized that human capital is essential to sustaining a competitive economy at high and rising living standards. Yet acceptance of persistent high unemployment, stagnant wages, and other indicators of declining job quality suggests that policymakers and employers undervalue human capital.
openaire +4 more sources
Advanced Science, EarlyView.Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu +12 more
wiley +1 more source
Clinical and Experimental Obstetrics & GynecologyBackground: This study aimed to investigate the role of nicotinamide adenine dinucleotide (NAD+) in endometrial decidualization prior to embryo implantation and to elucidate the underlying mechanism.
Ming-hui Liu, Yao Fu, Shuo Han
doaj +1 more source
HUMAN CAPITAL DAN KENDALA PENERAPANNYA DALAM LAPORAN KEUANGAN
, 2012 Human Capital has been examined in several countries. Financial statement users require information to hit an asset because it is important. However, in another hand, it is frequently to be ignored.
Arsalan, Syakieb
core
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Advanced Science, EarlyView.Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Coronary Angiography in Patients With Left Ventricular Hypertrabeculation/Noncompaction [PDF]
Texas Heart Institute JournalBackground Left ventricular hypertrabeculation/noncompaction (LVHT) is a cardiac abnormality of unknown pathogenesis, frequently associated with neuromuscular disorders. The relevance of coronary artery disease (CAD) in LVHT is largely unknown.
Nicolas de Cillia, MD +5 more
doaj +1 more source
The human as capital? A contribution to the critique of the theory of human capital [PDF]
Annales. Etyka w Życiu Gospodarczym, 2017 In modern economic theories, human qualities are treated as autonomous production factors, which are called “human capital”. However, these theories provide no description of the relationship between human capital and the man who is its “bearer”, nor an explanation of the formation process of that capital.
openaire +4 more sources