Results 111 to 120 of about 827,198 (306)

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Impact Analysis of Changes in Human Resource Capital on Economic Development - from Gravely Underdeveloped to Highly Developed Societies [PDF]

This research encompasses 177 countries around the world with the data on human resource variables for the year 2005. The countries have been put into four groups: gravely underdeveloped, developing, developed, and highly developed.
Boris Crnkovic, Zeljko Pozega
core  

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

An Intertemporal Model of Rational Criminal Choice [PDF]

This research presents a dynamic model of crime in which agents anticipate future consequences of their actions. Current period decisions affect future outcomes by a process of capital accumulation.
Jenny Williams
core  

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

The Features of Regional Human Capital Development

Studia Regionalne i Lokalne
The article focuses on identifying the specifics of the relationship between human capital and the quality of economic development across regions and the world as a whole.
Olena Stryzhak
doaj   +1 more source

THE IMPACT OF HUMAN CAPITAL ON TOTAL FACTOR PRODUCTIVITY IN INDUSTRIAL SECTOR IN THE EAST AZARBAIJAN PROVINCE [PDF]

فصلنامه پژوهش‌های اقتصادی ایران, 2010
Productivity improvement is one of the important factors in economic growth.. This paper attempts to study the impact of human capital on Total Factor Productivity in the industrial sector of East Azarbaijan Province in Iran during the period 1374-1385 ...
Ali Emami Meybodi, Musa Khoshkalam Khosroshahi, Rohallah Mahdavi   +2 more
doaj  

Crescimento dos vales do Tietê e Paraná: um enfoque de estoques de capitais [PDF]

The study aimed at identifying factors limiting the Tietê and Paraná valleys economic growth. Specifically, it analyzed the importance of the capital stocks for economic growth of these and the other counties in São Paulo State.
Bernardes, Elaine Mendonca, Pavarina, Paula R. de J. Pinsetta, Peres, Fernando Curi   +2 more
core   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

3.1. HUMAN CAPITAL INDEX TRACK DEVELOPMENT MODEL IN DIGITAL ECONOMY

Audit and Financial Analysis, 2020
Трансформация; цифровая экономика; цифровизация; индекс человеческого капитала; матрица сценариев; треки; человеческий капитал; трудовые ресурсы; цифровая революция; гиг-экономика; автоматизация; компоненты человеческого капитала.Близкий Роман Сергеевич The ...
openaire   +1 more source