Results 131 to 140 of about 827,198 (306)

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

A New Index of Human Capital to Predict Economic Growth

open access: yes, 2018
The accumulation of knowledge required to produce economic value is a process that often relates to nations economic growth. Such a relationship, however, is misleading when the proxy of such accumulation is the average years of education. In this paper, we show that the predictive power of this proxy started to dwindle in 1990 when nations schooling ...
Laverde, Henry   +2 more
openaire   +2 more sources

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

open access: yesAdvanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang   +9 more
wiley   +1 more source

Governance and Regulation of New Economy Companies: The Role of Human Capital [PDF]

open access: yes
There has been much publicity surrounding “new economy” companies, a term embracing “dot.com”, “high-tech” and “innovative high growth” companies, amongst others.
Copp, Stephen   +3 more
core  

Empirical analysis of regional economic performance in Russia : human capital perspective [PDF]

open access: yes, 2012
Having shown the important role of the Russian economy in the ex-USSR region by causality tests, we proceed to empirical analysis of growth and performance of the Russian regions. A dynamic panel data approach enabled us to obtain elasticity coefficients
Kufenko, Vadim
core   +1 more source

A Socioeconomic Disaggregation of the World Bank Human Capital Index

open access: yes, 2019
This paper documents inequality in health and education outcomes by constructing an index of human capital disaggregated by quintiles of socioeconomic status (SES) for a sample 51 mostly low- and middle-income countries.
D'Souza, Ritika   +2 more
openaire   +2 more sources

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Species Dependent Toxicity Comparison Outcome

open access: yesAdvanced Science, EarlyView.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao   +7 more
wiley   +1 more source

Central Asia : Mapping Future Prospects [PDF]

open access: yes
Central Asia has emerged as one of the worlds fastest growing regions since the late 1990s and has shown notable development potential. This is significant for a region comprising largely of small landlocked economies with no access to the sea for trade.
Ganeshan Wignaraja, Malcolm Dowling
core   +1 more source

Productivity growth, human capital and distance to frontier in Sub-Saharan Africa [PDF]

open access: yes, 2010
Using the Malmquist productivity index and panel data methods, we study the role of total human capital and its composition in the technological "catch-up" process and productivity growth via the channels of innovation and adoption of technology in a ...
Danquah, Michael   +2 more
core  

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