Results 141 to 150 of about 3,157,420 (313)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Human Rights in Lithuania, November 2008
The purpose of the study: to analyze the Lithuanian system for the protection of human rights, identify how people protect violated (abused) rights and how they assess effectiveness of various institutions assuring the human rights. Major investigated
Human Rights Monitoring Institute
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
BMC Infectious DiseasesBackground Human adenovirus (HAdV) is an important pathogen causing acute respiratory infection (ARI) in children. Many countries, including China, have experienced sporadic or outbreaks related to HAdV-4, and death cases were reported. However, there is
Jinjin Wang +13 more
doaj +1 more source
Human Rights in Lithuania, November 2010
The purpose of the study: to analyze the Lithuanian system for the protection of human rights, identify how people protect violated (abused) rights and how they assess effectiveness of various institutions assuring the human rights. Major investigated
Human Rights Monitoring Institute
core
, 2008 In analyzing and describing the contribution and the role of an important international judicial body such as the International Court of Justice (ICJ, World Court, or simply the Court) in the interpretation and the development of international human ...
Zyberi, G. +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Possible role of lens collagen in cataractogenesis
Indian Journal of Ophthalmology, 1997 The solubility characteristics of collagen in human cataractous eye lenses were studied in relation to age. Post-operative cataractous lenses were collected form eye camps in Phulbani district of Orissa.
Mishra Gitanjali, Das Gagan, Behera H
doaj
Human Arm Impedance and EMG in 3D
, 2009 This paper shows the relationship between EMG signals and human arm stiffness, measured in 3-D space. Preliminary results demonstrate the viability of this approach, which can then be used to measure human arm impedance from EMG only.
Patrick, van der Smagt +2 more
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source