Results 121 to 130 of about 3,157,420 (313)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Clinical and epidemiological characteristics of human metapneumovirus in children in Hangzhou, China

Virology Journal
This study aims to describe the epidemiology and genotypic diversity of human metapneumovirus (HMPV) in hospitalized children with pneumonia in Hangzhou, Zhejiang, China. From February 2022 to January 2023, nasopharyngeal swabs from hospitalized children
Ya-jun Guo, Qin-rui Lai, Jie Song, Qun Wang, Bo-fei Hu, Ya-ling Li, Ying-shuo Wang, Wei Li, Xiang-zheng Ma   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

No convincing evidence outgroups are denied uniquely human characteristics: Distinguishing intergroup preference from trait-based dehumanization.

Cognition, 2021
Enock FE, Flavell JC, Tipper SP, Over H.
europepmc   +1 more source

Postmortem human brain donor characteristics.

, 2019
Postmortem human brain donor characteristics.
Jonathan Sirovatka (7534679), Constance DiAngelo (7534691), Joel E. Kleinman (7534697), Mary M. Herman (2459539), Dawn Zulauf (7534688), Michelle I. Mighdoll (7534670), Thomas M. Hyde (7534694), Stephen B. Thomas (7534676), Andrew E. Jaffe (7534673), David R. Fowler (7534685), Amy Deep-Soboslay (67661), Jewell P. King (7534682)   +11 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Epidemiological Characteristics and Genotype Distribution of Human Papillomavirus Among Women of Different Ethnic Groups in the Yili Region: A Retrospective Study of 13,915 Women

International Journal of Women's Health
Huizi He,1,* Xiaoli Hou,1,* Hulkar Bahtiyar,1 Meier Tuhetamishi,1 Tingting Bian1,2 1Department of Pathology, Friendship Hospital of Ili Kazak Autonomous Prefecture, Yining, Xinjiang Uygur Autonomous Region, People’s Republic of China ...
He H, Hou X, Bahtiyar H, Tuhetamishi M, Bian T   +4 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Human Psychological Characteristics versus Animal Characteristics

Psychology, 2013
The role of biology in psychology changes from animals to humans. Biology determines animal behaviour in natural environments. For humans the biological forces changes to an energizing function. They recede in the background and the higher psychological functions govern consciousness and behavior.
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source