Results 121 to 130 of about 7,263,341 (302)
Clinical and epidemiological characteristics of human metapneumovirus in children in Hangzhou, China
Virology JournalThis study aims to describe the epidemiology and genotypic diversity of human metapneumovirus (HMPV) in hospitalized children with pneumonia in Hangzhou, Zhejiang, China. From February 2022 to January 2023, nasopharyngeal swabs from hospitalized children
Ya-jun Guo +8 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Nineteen sixty-seven behavioral model of man - His chains revealed [PDF]
Dynamic characteristics of physical-chemical systems in human behavior, and structural nature of ...
Iberall, A., Mc Culloch, W.
core +1 more source
Human Psychological Characteristics versus Animal Characteristics
Psychology, 2013 The role of biology in psychology changes from animals to humans. Biology determines animal behaviour in natural environments. For humans the biological forces changes to an energizing function. They recede in the background and the higher psychological functions govern consciousness and behavior.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Normative Gait Databases in Praxis
Advances in Electrical and Electronic Engineering, 2005 The gait analysis history brought a lot of methods and methodologies. It became a standard to collect data and create databases of human gait characteristics. One of the reasons is to derive standard deviations to be able compare patients’ data. The most
Jaroslav Majernik, Dusan Simsik
doaj
The Distribution of the Gender Wage Gap in Italy: Does Education Matter? [PDF]
In this paper we evaluate the wage gap due to differences in rewards to characteristics by studying the entire distribution of the individual unexplained wage gap.
Donata Favaro +2 more
core