Results 101 to 110 of about 2,883,463 (264)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

No convincing evidence outgroups are denied uniquely human characteristics: Distinguishing intergroup preference from trait-based dehumanization.

Cognition, 2021
Enock FE, Flavell JC, Tipper SP, Over H.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Epidemiological Characteristics and Genotype Distribution of Human Papillomavirus Among Women of Different Ethnic Groups in the Yili Region: A Retrospective Study of 13,915 Women

International Journal of Women's Health
Huizi He,1,* Xiaoli Hou,1,* Hulkar Bahtiyar,1 Meier Tuhetamishi,1 Tingting Bian1,2 1Department of Pathology, Friendship Hospital of Ili Kazak Autonomous Prefecture, Yining, Xinjiang Uygur Autonomous Region, People’s Republic of China ...
He H, Hou X, Bahtiyar H, Tuhetamishi M, Bian T   +4 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Normative Gait Databases in Praxis

Advances in Electrical and Electronic Engineering, 2005
The gait analysis history brought a lot of methods and methodologies. It became a standard to collect data and create databases of human gait characteristics. One of the reasons is to derive standard deviations to be able compare patients’ data. The most
Jaroslav Majernik, Dusan Simsik
doaj  

Human Psychological Characteristics versus Animal Characteristics

Psychology, 2013
The role of biology in psychology changes from animals to humans. Biology determines animal behaviour in natural environments. For humans the biological forces changes to an energizing function. They recede in the background and the higher psychological functions govern consciousness and behavior.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Universality of human rights: general theoretical characteristics

Bulletin of Kharkiv National University of Internal Affairs
The article examines the general theoretical characteristics of universal human rights. It is noted that human rights are an integral part of human dignity, they define the essence of humanity, and represent the limits of state power in relation to the ...
Yu. A. Kholod
doaj   +1 more source