Results 111 to 120 of about 3,157,420 (313)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 2003 Virtuality would seem to offer certain advantages for human supervisory control. First, it could provide a physical analogue of the 'real world' environment. Second, it does not require control room engineers to be in the same place as each other.
Stanton, Neville A. +5 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Characteristics of human Ewing/PNET sarcoma models
Annals of Saudi Medicine, 2011 Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical
Teicher Beverly +5 more
doaj
The Human Sexual Characteristics
International Journal of Recent Innovations in Medicine and Clinical ResearchThe sex glands are not only the site where sex cells (spermatozoa and ova) are formed, but also have a function of internal secretion, discharging sex hormones into the blood. These hormones fall into two groups: the male sex hormones or androgens, and female sex hormones or oestrogens (oestrus, the period of ovarian hormonal activity or the period of ...
Janos Vincze, Gabriella Vincze-Tiszay
openaire +1 more source
Characteristics of human islet donors.
, 2016 Characteristics of human islet donors.
M. A. Chauvin (849618) +14 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Intra-Firm Human Capital Externalities in Tunisia [PDF]
In this case-study, we use matched worker-firm Tunisian data to elicit the roles of intra-firm human capital and modern firm features in worker remunerations. We show that the estimated return to education in wage equations is not modified when replacing
Christophe Muller, Christophe J. Nordman
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2013 The purpose of this study was to investigate the difference in the amount of spin that can be generated during a controlled golf shot, as a result of the 2010 rule change regarding restrictions applied to the design of the grooves on the clubface ...
Wilkinson, Mick +2 more
core