Results 121 to 130 of about 7,502,790 (265)
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar +3 more
wiley +1 more source
Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li +9 more
wiley +1 more source
Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Muhammad Hassaan Javaid +4 more
wiley +1 more source
ABSTRACT Premature constriction of the ductus arteriosus accompanied by the dilation of the pulmonary trunk constitutes a rare congenital heart anomaly that may be underestimated and can result in fetal hydrops and ultimately death if not treated; therefore, it necessitates fetal post‐mortem evaluation in all cases of legal abortion or fetal death.
Nazari Mohadeseh +2 more
wiley +1 more source
Epigallocatechin Gallate From Tea Delays Oocyte Aging After Ovulation in Mice
In this study, we find that EGCG delays post‐ovulatory oocyte aging and improves the quality of aged oocytes. EGCG may reduce ROS levels in aged oocytes by the NRF2‐KEAP1 pathway. The embryo developmental potential of aged oocytes is also increased by EGCG. ABSTRACT In clinic, once the ovulated oocytes cannot be fertilized timely, they begin to undergo
Jing Lin +9 more
wiley +1 more source
ABSTRACT Background and Aims Azoospermia, defined as the complete absence of sperm in the ejaculate, is a major cause of male infertility and is classified into obstructive and non‐obstructive forms. While obstructive azoospermia is primarily mechanical in origin, non‐obstructive azoospermia (NOA) is characterized by impaired spermatogenesis and is ...
Faraz Khakshour +4 more
wiley +1 more source
FIGO staging for gestational trophoblastic neoplasia: 2026
Abstract Gestational trophoblastic neoplasia (GTN) encompasses a wide range of diseases, which include choriocarcinoma, placental site trophoblastic tumor, epithelioid trophoblastic tumor, and post‐molar persistent or rising levels of human chorionic gonadotrophin.
Hextan Y. S. Ngan +10 more
wiley +1 more source
Testis‐Sparing Surgery for Metachronous Testicular Tumor Following Orchiectomy
ABSTRACT Introduction For metachronous bilateral testicular tumors occurring in young adulthood, the post‐treatment quality of life must be considered when making treatment decisions. Case Presentation A 46‐year‐old man presented to our hospital with a chief complaint of two bean‐sized hard masses palpable in the right testis.
Motoi Tobiume +9 more
wiley +1 more source
Metastatic Testicular Cancer Complicated by Myelodysplastic Syndrome
ABSTRACT Introduction The coexistence of testicular cancer and hematopoietic disorders is rare, and reports on optimal treatment strategies are limited. Here, we present a case of metastatic testicular cancer associated with myelodysplastic syndrome. Case Presentation A 24‐year‐old man with pancytopenia underwent right orchiectomy for a right scrotal ...
Nobuhiko Shimizu +9 more
wiley +1 more source

