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Antibodies to human chorionic gonadotropin in humans
Clinica Chimica Acta, 1981Very few observations have been published about the development of antibodies against gonadotropins in the human. Human FSHand hCG-antibodies have been detected in a patient with isolated FSH-deficiency after human menopausal gonadotropin administration [l], or after human menopausal (hMG) and chorionic gonadotropin (hCG) administration in women with ...
K, Musch, A S, Wolf, C, Lauritzen
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Studies of Human Chorionic Gonadotropin
1971Publisher Summary This chapter focuses on human chorionic gonadotropin (HCG), a glycoprotein hormone produced by the placenta that appears in significant quantities in the urine during the first trimester of pregnancy. The mean level of urinary HCG produced during the first trimester is 30,000–50,000 IU in 24 hours, equivalent to a maximum of ...
R E, Canfield +4 more
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2021
HCG is a hormone unique to gestation, however, it may be raised in other pathological conditions as well. Human chorionic gonadotropin (hCG) is a placental hormone secreted after implantation and is commonly detected by urine gravindex test. It interacts with the LHCG receptor of the ovary and maintains the corpus luteum during initial weeks of ...
Ashok Kumar Padhy +2 more
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HCG is a hormone unique to gestation, however, it may be raised in other pathological conditions as well. Human chorionic gonadotropin (hCG) is a placental hormone secreted after implantation and is commonly detected by urine gravindex test. It interacts with the LHCG receptor of the ovary and maintains the corpus luteum during initial weeks of ...
Ashok Kumar Padhy +2 more
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Immunochemistry of Human Chorionic Gonadotropin
1984In states of gestational trophoblastic disease, knowledge of the immunochemistry of human chorionic gonadotropin (hCG) is principally of value in relation to its use as a diagnostic tool and as a marker for the persistence of disease activity during chemotherapy (1, 2).
R E, Canfield +3 more
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Biosynthesis of Human Chorionic Gonadotropin*
Endocrine Reviews, 1980HUMAN chorionic gonadotropin (hCG) is a glycoprotein hormone normally secreted by trophoblastic cells of the placenta during pregnancy. Trophoblastic tumors and some nontrophoblastic tumors also secrete hCG and/or its α- or β-subunit. This review emphasizes a number of aspects, some controversial, of hCG biosynthesis and secretion that have received ...
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Human chorionic gonadotropin tests
Expert Review of Molecular Diagnostics, 2009Human chorionic gonadotropin (hCG) is not a single biological molecule. There is the regular form of hCG produced by differentiated syncytotrophoblast cells (regular hCG). This hormone primarily functions to maintain the myometrial and decidual spiral arteries, or the vascular supply of the placenta during the full course of pregnancy ...
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Archives of Andrology, 1988
We measured testicular human chorionic gonadotropin (hCG) receptors in 30 infertile men either before or 1, 3, 5, 7, or 14 days after a single administration of 5000 IU of hCG. For 5 days the administration of hCG significantly reduced the testicular binding of 125I-hCG compared with that of the testes before administration.
M, Namiki +8 more
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We measured testicular human chorionic gonadotropin (hCG) receptors in 30 infertile men either before or 1, 3, 5, 7, or 14 days after a single administration of 5000 IU of hCG. For 5 days the administration of hCG significantly reduced the testicular binding of 125I-hCG compared with that of the testes before administration.
M, Namiki +8 more
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Hormone Research, 2008
Changes in rat and human testicular human chorionic gonadotropin (hCG) binding sites induced by hCG were estimated in vivo and in vitro. After a single administration of hCG, the specific 125I-hCG bindings were significantly reduced for 7 and 5 days in rat and human testes, respectively.
M, Namiki +8 more
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Changes in rat and human testicular human chorionic gonadotropin (hCG) binding sites induced by hCG were estimated in vivo and in vitro. After a single administration of hCG, the specific 125I-hCG bindings were significantly reduced for 7 and 5 days in rat and human testes, respectively.
M, Namiki +8 more
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Human chorionic gonadotropin in commercial human menopausal gonadotropin preparations
Fertility and Sterility, 1993Several studies indicated the presence of an hCG-immunoreactive substance in commercial hMG preparations. Because hCG represents LH activity with a relatively very long half-life, differences between hMG preparations with respect to hCG content could imply clinical differences.
P G, Stokman +5 more
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Human chorionic gonadotropin and malignant mesothelioma
Cancer, 1979A 56-year-old male presented with ascites and gynecomastia. Laparoscopy demonstrated peritoneal tumors which were biopsied. Conventional histology and electron microscopy revealed the tumor to be a malignant mesothelioma. The ascitic fluid and tumor cell lysate, but not serum, contained hCG by specific assay, and the immunoreactive hCG had ...
S, Rich +4 more
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