Nanoparticles Functionalized with Polymer Brushes for Gene Delivery
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley +1 more source
Cell DNA Replication as a Function in the Synthesis of Human Cytomegalovirus
Stephen C. St. Jeor, Richard Hutt
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Immunoglobulin G to Virus-Specific Early Antigens in Congenital, Primary, and Reactivated Human Cytomegalovirus Infections [PDF]
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Human Cytomegalovirus Antigen Presentation by HLA-G in Infected Cells. [PDF]
Altadill M+11 more
europepmc +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen+2 more
wiley +1 more source
Characterization of human cytomegalovirus infection dynamics in human microglia. [PDF]
Nuevalos Guaita M+9 more
europepmc +1 more source
Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus. [PDF]
Karen K. Biron+6 more
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Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni+10 more
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Effect of host telomerase inhibition on human cytomegalovirus. [PDF]
Cavanaugh CM+7 more
europepmc +1 more source
Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)
The multicolumn countercurrent solvent gradient purification (MCSGP) method was evaluated as a method to enhance the separation of empty and full capsids during AAV2 purification. The results demonstrated an enrichment of full AAV2 particles using MCSGP.
Julia M. Müller+9 more
wiley +1 more source