Results 151 to 160 of about 9,097,628 (294)

From Molecular Pathogenesis to Therapeutic Innovations in Human Cytomegalovirus Research. [PDF]

Pathogens
Damour A, Larribau M, Ligat G.
europepmc   +1 more source

DUSP26 Regulated by YY1 Lactylation Couples Osteogenesis and Angiogenesis by Dephosphorylating PMPCB at Y141 and Activating Mitophagy in BMSCs

Advanced Science, EarlyView.
p300‐associated YY1 lactylation promotes DUSP26 expression in BMSCs. By regulating PMPCB phosphorylation and PINK1 processing, DUSP26 supports mitophagy, osteogenic differentiation, and pro‐angiogenic factor secretion. BMSC‐derived exosomes carrying a RUNX2 promoter‐driven DUSP26 plasmid favor osteogenic‐lineage transgene expression, partially ...
Yunpeng Lv, Feng Wu, Xiongjie Liang, Chong Liu, Wenhui Guo, Kejian Zhang, Jiawen Niu, Wenjie Jiang, Hongjian Xu, Anlong Jiang, Yang Zheng, Enming Yu, Xintao Wang, Jinglong Yan, Jingjun Xia, Chengchao Song   +15 more
wiley   +1 more source

Heparan Sulfate Differentially Regulates Fibroblast Binding by Extracellular Vesicles and Human Cytomegalovirus. [PDF]

J Extracell Vesicles
Bokun V, Di Maio A, Zhang Y, Chai W, Holder B, Liu Y.   +5 more
europepmc   +1 more source

Adaptive Cellular Responsiveness to Electrical Stimulation at the Skin‐Electrode Interface

Advanced Science, EarlyView.
This study presents an adaptive bioelectronic response in which sustained electrical stimulation (ES) upregulates voltage‐gated calcium channels (VGCCs) and enhances cellular sensitivity to subsequent ES at the skin‐device interface. VGCC‐associated adaptive sensitization promotes regenerative wound‐healing responses in vivo, including accelerated ...
Yeon Jae Chang, Soon Jin Choi, Khandoker Asiqur Rahaman, Tae Kyoung Lee, Gwangbin Lee, Jaeyeon Jun, Hyeon‐Jeong Lee, Hophil Min, Hojeong Jeon, Jung Keun Hyun, Hyung‐Seop Han, Jimin Park   +11 more
wiley   +1 more source

Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights. [PDF]

Rev Med Virol
AlQahtani HY, Aleanizy FS, Alqahtani FY.
europepmc   +1 more source

Human Cytomegalovirus (HCMV) – Revised [PDF]

Transfusion Medicine and Hemotherapy, 2010
Schottstedt, Volkmar, Blümel, Johannes, Burger, Reinhard, Drosten, Christian, Gröner, Albrecht, Gürtler, Lutz G., Heiden, Margarethe, Hildebrandt, Martin, Jansen, Bernd, Montag-Lessing, Thomas, Offergeld, Ruth, Pauli, Georg, Seitz, Rainer, Schlenkrich, Uwe, Strobel, Johanna, Willkommen, Hannelore, Wirsing von König, Carl-Heinz   +16 more
openaire   +3 more sources

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

Repurposing ritonavir to induce proteasomal degradation of IE1 for inhibition of human cytomegalovirus replication. [PDF]

PLoS Comput Biol
Liu W, Shi Y, Guo X, Lou C, Xie Z, Shen Y, Zhang L, Mao S, Xue X, Feng S.   +9 more
europepmc   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

Mapping the monoclonal antibody landscape of human cytomegalovirus. [PDF]

J Virol
McClave MK, Heldwein EE.
europepmc   +1 more source